2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-16672
    AVX 13616 900814-48-4 98%
    AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens.
    AVX 13616
  • HY-16773
    Vedroprevir 1098189-15-1 98%
    Vedroprevir (GS-9451) is an inhibitor for HCV NS3/4A protease with an IC50 of 3.2 nM. Vedroprevir is also an inhibitor for breast cancer resistant protein (BCRP) with an IC50 of 1.4 μM. Vedroprevir inhibits P-gp, MRP1 and MRP2 with IC50 of 34, 14.9 and 12 μM, respectively. Vedroprevir exhibits good pharmacokinetic characteristics in rats and dogs.
    Vedroprevir
  • HY-16913
    Desferriferrithiocin 76045-30-2 98%
    Desferriferrithiocin (CGP 23841A), a microbial iron chelator, inhibits the growth of P. falciparum in a dose dependent way.
    Desferriferrithiocin
  • HY-16955
    Plazomicin 1154757-24-0 98%
    Plazomicin (ACHN 490) is a semi-synthetic aminoglycoside Antibiotic. Plazomicin acts as a substrate for Aminoglycoside acetyltransferase and Aminoglycoside phosphotransferase. Plazomicin is not modified by various common aminoglycoside-modifying enzymes. Plazomicin selectively inhibits MATE2-K. Plazomicin exhibits activity against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales.
    Plazomicin
  • HY-17517
    Tiadinil 223580-51-6 99.84%
    Tiadinil is a systemic acquired resistance (SAR) inducer, plant elicitor and antifungal agent. Tiadinil promotes the production of herbivore-induced plant volatiles in Camellia sinensis (tea plant). Tiadinil inhibits mycelial growth, spore germination and germ tube elongation of Stagonosporopsis citrulli in vitro. Tiadinil can be used in studies related to vine blight.
    Tiadinil
  • HY-17521
    Flumorph 211867-47-9 99.57%
    Flumorph (SYP-L190) is a carboxylic acid amide fungicide. Flumorph inhibits the polar growth of Phytophthora melonis by disrupting the arrangement of filamentous actin. Flumorph can be used to study Phytophthora melonis infection.
    Flumorph
  • HY-17523
    Athidathion 19691-80-6 98%
    Athidathion (GS-13006) is an organophosphate insecticide.
    Athidathion
  • HY-17524
    Benoxafos 16759-59-4 98%
    Benoxafos (HOE 2910) is an insecticide.
    Benoxafos
  • HY-17525
    Bethoxazin 163269-30-5 98.45%
    Bethoxazin(Bethoguard) is a new broad spectrum industrial microbicide with applications in material and coating preservation.
    Bethoxazin
  • HY-17619
    Ravidasvir 1242087-93-9 98%
    Ravidasvir (PPI-668) is an orally active pan-genotypic NS5A inhibitor and antiviral agent. Ravidasvir exhibits antiviral activity against HCV genotypes 1 to 6, with EC50 values ranging from 0.04 to 1.14 nM. Ravidasvir shows no or extremely low activity against feline infectious peritonitis virus type II. Ravidasvir can be used in research related to hepatitis C virus infection.
    Ravidasvir
  • HY-17656
    C3361 91042-00-1
    C3361 is a moderate specific Plasmodium falciparum hexose transporter 1 (PfHT1) and Plasmodium berghei hexose transporter 1 (PbHT1) inhibitor with Ki values of 8.6 and 9.4 μM. C3361 inhibits TgGT1 with a Ki of 82 μM. C3361 attenuates hepatic (IC50 = 15 μM) and ookinete development of P. berghei. C3361 can suppress the growth of blood-stage parasites. C3361 can be used for the research of infection, such as malaria.
    C3361
  • HY-17671
    Cholesterol heptanoic acid 103003-24-3 98%
    Cholesterol heptanoic acid is a lipophilic Cholesterol (HY-N0322) derivative. Cholesterol heptanoic acid can combine with peptides (such as peptides P1 and P2) to form lipopeptides, which possess antiviral activity. Cholesterol heptanoic acid can be used for research of HIV infection.
    Cholesterol heptanoic acid
  • HY-17677
    Antiviral agent 78 445032-93-9
    Antiviral agent 78 (Compound 27) is an antiviral agent. Antiviral agent 78 shows IC50 values of 11.22, 78.54 and 71.49 μM against 2019-nCoV, Ebola virus replicon and avian influenza virus A/Guangzhou/99. Antiviral agent 78 can be used for research of virus infection.
    Antiviral agent 78
  • HY-18564
    HCV-IN-3 1401839-25-5 98%
    HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor, with an IC50 of 20 μM, a Kd of 29 μM.
    HCV-IN-3
  • HY-18704
    Cyslabdan 956507-17-8 98%
    Cyslabdan ((+)-Cyslabdan) is a novel compound with the potential to enhance the activity of imipenem against methicillin-resistant Staphylococcus aureus. Cyslabdan exerts its antibacterial effect by inhibiting the synthesis of pentapeptide cross-links.
    Cyslabdan
  • HY-19071
    BK-218 110008-56-5 98%
    BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs.
    BK-218
  • HY-19111
    R-82150 126320-77-2 98%
    R-82150 (TIBO-R 82150) is an HIV-1 reverse transcriptase inhibitor that blocks the reverse transcription of viral RNA by binding to the non-substrate binding site of reverse transcriptase, thereby inhibiting viral replication. R-82150 does not inhibit the replication of HIV-2, other RNA viruses, and DNA viruses.
    R-82150
  • HY-19135
    A-77003 134878-17-4 98%
    A-77003 is an inhibitor for HIV protease, with IC50 of 0.1 to 0.2 μg/ml, for HIV-1 and HIV-2 protease. A-77003 exhibits high levels of antiretroviral activity and low cytotoxicity in vitro.
    A-77003
  • HY-19143
    L-697639 135525-77-8 98%
    L-697639 is an inhibitor for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 20-400 nM (in a template-primer-dependent manner). L-697639 exhibits antiviral activity, that inhibits 95% HIV-1 infection at concentrations of 12-200 nM in human T lymphocyte cultures.
    L-697639
  • HY-19147
    BMY-43748 132195-65-4 98%
    BMY-43748 is a promising antibacterial agent, exhibiting great in vitro and in vivo antibacterial activity.
    BMY-43748
Cat. No. Product Name / Synonyms Application Reactivity