2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-107009
    CTC 96 149754-11-0 98%
    CTC 96 is an antiviral agent, showing inhibitory effects particularly on herpes viruses and adenoviruses. CTC 96 directly blocks the fusion process between the viral envelope and the cell membrane, preventing the entry of viral nucleic acids and proteins into the cells. CTC 96 can completely block the penetration and intercellular transmission of HSV-1, preventing the synthesis of viral proteins and mRNA. CTC 96 exhibits significant anti-adenovirus activity in rabbit eye models. CTC 96 is also effective against varicella-zoster virus (VZV) and vesicular stomatitis virus (VSV). CTC 96 can be used for broad-spectrum antiviral research.
    CTC 96
  • HY-107025
    Cf1743 319425-66-6 99.44%
    Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK).
    Cf1743
  • HY-107053
    BC-1175 635292-67-0 98%
    BC-1175 (CB-181963) is a novel cephalosporin and antibacterial agent. CB-181963 displays strong binding to altered PBP 2a. CB-181963 demonstrates marked efficacy against MRSA, Klebsiella pneumoniae, Streptococcus pneumoniae, and Escherichia coli.
    BC-1175
  • HY-107142
    RM-5038 1349090-91-0 98%
    RM-5038 is a thiazolide antivirus agent. RM-5038 can induce innate immunity and reduce HIV replication.
    RM-5038
  • HY-107143
    BL-8030 1285533-27-8 98%
    BL-8030 is an anti-HCV agent. BL-8030 can be used for the research of infection.
    BL-8030
  • HY-107163
    CS 461 115948-58-8 98%
    CS 461 is a cephalosporin antibiotic. CS 461 shows potent and well-balanced antibacterial activity against Gram-positive and Gram-negative bacteria including some β-lactamase producing species. CS 461 can be used for the research of infection.
    CS 461
  • HY-107211
    Echinocandin B nucleus 79411-15-7 98%
    Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B (HY-125723) deacylase. Echinocandin B nucleus serves as an intermediate for the synthesis of semi-synthetic antifungal agents.
    Echinocandin B nucleus
  • HY-107331
    Chlorproguanil 537-21-3 98%
    Chlorproguanil is an antifolate with an IC50 of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria.
    Chlorproguanil
  • HY-107468
    PL-100 612547-11-2 98%
    PL-100 is a potent HIV-1 protease inhibitor with a Ki of 36 pM and an EC50 of 16 nM. PL-100 inhibits viral replication by suppressing HIV-1 protease activity and demonstrates excellent antiviral efficacy against drug-resistant HIV strains. PL-100 can be used in research on drug-resistant HIV disease.
    PL-100
  • HY-107772
    NC-1175 hydrochloride 214834-79-4 98%
    NC-1175 hydrochloride is an antifungal agent targeting cell membrane H+-ATPase. NC-1175 hydrochloride can be used for the research of infection.
    NC-1175 hydrochloride
  • HY-107852
    Demeton-S-methyl sulfone 17040-19-6 98%
    Demeton-S-methyl sulfone is an organophosphorus insecticide metabolite.Demeton-S-methyl sulfone serves as a substrate for metabolic breakdown.Demeton-S-methyl sulfone forms via oxidation of demeton S-methyl sulfoxide in sugar-beet cell suspension cultures.Demeton-S-methyl sulfone undergoes thioester bond cleavage, producing ethanethiols that convert into S-methylated compounds or S-glucosides.
    Demeton-S-methyl sulfone
  • HY-108002
    A 33903 70890-53-8 98%
    A 33903 is a respiratory syncytial virus (RSV) replication inhibitor. A 33903 can be used for the research of RSV-infection.
    A 33903
  • HY-108018
    MK 6325 1263814-52-3 98%
    MK 6325 is a HCV NS3/4a protease inhibitor. MK 6325 displays the broad genotype and mutant potency. MK 6325 can be used for the research of infection.
    MK 6325
  • HY-108021
    HT-61 936622-80-9 98%
    HT-61 is a quinolone antibacterial agent. HT-61 exhibits bactericidal activity against gram-positive bacteria including methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). HT-61 can enhance the effect of Tobramycin (HY-B0441) against Pseudomonas aeruginosa.
    HT-61
  • HY-108023
    SP187 hydrochloride 1333144-07-2 98%
    SP187 hydrochloride (MON-DNJ hydrochloride; UV4 hydrochloride) is an orally active, host-targeting iminosaccharide against filovirus infection. SP187 hydrochloride inhibits endoplasmic reticulum glucosidase. SP187 hydrochloride exhibits antiviral and Dengue Virus activity in vivo. SP187 hydrochloride can be used in antiviral and dengue research.
    SP187 hydrochloride
  • HY-108029
    Deldeprevir sodium 1298053-61-8 98%
    Deldeprevir (ACH-2684; Neceprevir) sodium is a HCV NS3/4A protease inhibitor and resistance inhibitor. Deldeprevir sodium exhibits activity against wild-type genotype 1a and 1b HCV, including mutant strains resistant to other NS3 protease inhibitors. Deldeprevir sodium blocks the emergence of HCV mutant strains resistant to ACH-3422 in vitro, with enhanced efficacy when used in triple combination with ACH-3422 and ACH-3102 (HY-124182). Deldeprevir sodium shows additive antiviral potency when combined with ACH-3422, and exerts antiviral activity against HCV replicons carrying ACH-3102. Deldeprevir sodium is applicable to research related to hepatitis C.
    Deldeprevir sodium
  • HY-108053
    CDRI-97/78 372960-05-9 98%
    CDRI-97/78 is an antimalarial agent. CDRI-97/78 has phototoxicity and can induce cell apoptosis and G2/M phase arrest. CDRI-97/78 can be used for the research of infection.
    CDRI-97/78
  • HY-108080
    BAL-0019764 404824-79-9 98%
    BAL-0019764 is an iron carrier monocyclic β-lactam with broad-spectrum β-lactase inhibition ability. BAL-0019764 has inhibitory activity against various Gram negative bacteria. BAL-0019764 is commonly used in the study of bacterial infections.
    BAL-0019764
  • HY-108191
    Paldimycin A 101411-70-5 98%
    Paldimycin A (Antibiotic 273a1α) is an antibiotic derived from Streptomyces paulus, primarily targeting Gram-positive bacteria. Paldimycin A exerts its antibacterial effects by interfering with bacterial protein synthesis and cell membrane function.
    Paldimycin A
  • HY-108255
    HIV-1 inhibitor-60 1443461-21-9 98%
    HIV-1 inhibitor-60 (compound 45) is an HIV inhibitor with the potential for the research of infection diseases.
    HIV-1 inhibitor-60
Cat. No. Product Name / Synonyms Application Reactivity