2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1074
    Warangalone 4449-55-2
    Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC50 of 3.5 μM.
    Warangalone
  • HY-N1147
    Tirotundin 56377-67-4
    Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ.
    Tirotundin
  • HY-N1177
    Taraxerone 514-07-8 99.95%
    Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively.
    Taraxerone
  • HY-N1187
    Syzalterin 94451-48-6 99.05%
    Syzalterin is an inhibitor of NO production with an IC50 of 1.87 μg/mL.
    Syzalterin
  • HY-N1203
    (5α)-Stigmastane-3,6-dione 22149-69-5
    (5α)-Stigmastane-3,6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle. Antimicrobial Activity..
    (5α)-Stigmastane-3,6-dione
  • HY-N1234
    Smyrindioloside 87592-77-6 99.32%
    Smyrindioloside is a natural product isolated from the bark of Streblus indicus.
    Smyrindioloside
  • HY-N1782
    3,4-O-Isopropylidene-shikimic acid 183075-03-8 99.48%
    3,4-O-Isopropylidene-shikimicn acid is a natural product that can be isolated from the whole plants of Hypericum wightianum. 3,4-O-Isopropylidene-shikimic acid has anti-inflammatory effect and antioxidant activities.
    3,4-O-Isopropylidene-shikimic acid
  • HY-N1922
    Mesaconine 6792-09-2 99.74%
    Mesaconinean, an ingredient from Aconitum carmichaelii Debx., has cardiac effect.
    Mesaconine
  • HY-N1955
    Protostemotinine 169534-85-4 99.36%
    Protostemotinine is an alkaloid isolated from the roots and rhizomes of Stemona sessilifolia.
    Protostemotinine
  • HY-N1965
    Gaultherin 490-67-5 99.44%
    Gaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-κB, MAPK, COX-2 (IC50 = 0.35 mg/mL), LOX (IC50 = 0.56 mg/mL) and HYAL (IC50 = 28.58 μg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin (HY-14654).
    Gaultherin
  • HY-N2030
    Perakine 4382-56-3 99.93%
    Perakine is an indole alkaloid with anti-inflammatory activities.
    Perakine
  • HY-N2154
    Rhodojaponin V 37720-86-8 99.96%
    Rhodojaponin V is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity. Rhodojaponin V is the C-14 acetylation product of Rhodojaponen III. L-Aspartic aicd sodium is commonly used in the study of inflammatory conditions.
    Rhodojaponin V
  • HY-N2170
    Acetylshengmanol Arabinoside 402513-88-6 ≥99.0%
    Acetylshengmanol Arabinoside is isolated from Cimicifugae rhizoma.
    Acetylshengmanol Arabinoside
  • HY-N2182
    Episyringaresinol 4'-O-β-D-glncopyranoside 137038-13-2 99.66%
    Episyringaresinol 4'-O-β-D-glncopyranoside (compound 22), isolated from Alhagi sparsifolia Shap, is a natural potential neuroinflammatory inhibitor.
    Episyringaresinol 4'-O-β-D-glncopyranoside
  • HY-N2185
    (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one 87095-74-7 98.0%
    (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one is the methylene chloride extract of Alpinia nutans, has antioxidant activity.
    (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one
  • HY-N2192
    Swertianolin 23445-00-3 ≥98.0%
    Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis.
    Swertianolin
  • HY-N2199
    Sotetsuflavone 2608-21-1
    Sotetsuflavone is a flavonoid that can be isolated from Cycas revolute. Sotetsuflavone inhibits phosphorylation of PI3K, Akt, mTOR, JNK, and p38 MAPK; modulates expression of Cyclin D1, CDK4, Bcl-2, Bax, cleaved caspases 3/9, MMP-9, TGF-β, STAT3, and β-catenin. Sotetsuflavone induces G0/G1 cell cycle arrest, apoptosis, autophagy, and intracellular ROS elevation, inhibits cancer cell proliferation. Sotetsuflavone inhibits tumor growth in mouse tumor xenograft models. Sotetsuflavone can be used for the research of non-small cell lung cancer and Crohn’s disease.
    Sotetsuflavone
  • HY-N2210
    5,7,4'-Trihydroxy-8-Methylflavanone 916917-28-7 99.94%
    5,7,4'-Trihydroxy-8-Methylflavanone (Compound 2) is a flavanone isolated from Qualea grandiflora.
    5,7,4'-Trihydroxy-8-Methylflavanone
  • HY-N2241
    Hosenkoside F 160896-45-7 99.90%
    Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina.
    Hosenkoside F
  • HY-N2249
    Hosenkoside A 156791-82-1 99.73%
    Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.
    Hosenkoside A
Cat. No. Product Name / Synonyms Application Reactivity