1. Metabolic Enzyme/Protease
  2. Aldehyde Dehydrogenase (ALDH)
  3. Taraxerone

Taraxerone 

Cat. No.: HY-N1177
Handling Instructions

Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively.

For research use only. We do not sell to patients.

Taraxerone Chemical Structure

Taraxerone Chemical Structure

CAS No. : 514-07-8

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Description

Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].

IC50 & Target

EC50: 512.42 μM (ADH); 500.16 μM (ALDH)[1]

In Vivo

Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1].
Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].

Molecular Weight

424.70

Formula

C₃₀H₄₈O

CAS No.

514-07-8

SMILES

CC1(C)C(CC[[email protected]]2(C)[[email protected]@]3([H])CC[[email protected]@]4(C)[[email protected]]5([H])CC(C)(C)CC[[email protected]@](C)5CC=C4[[email protected]@](C)3CC[[email protected]@]12[H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TaraxeroneAldehyde Dehydrogenase (ALDH)ALDHADHalcoholenhancerInhibitorinhibitorinhibit

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