2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N9375
    Kakkanin 63770-91-2 99.44%
    Kakkanin comes from the roots of O. henryi and can be used for the research of anti-inflammatory.
    Kakkanin
  • HY-N9437
    Betulin diacetate 1721-69-3
    Betulin diacetate, a triterpene and derivative of Betulin, is an anti-AID agent and also possesses anti-cancer activity.
    Betulin diacetate
  • HY-N9488
    Girinimbine 23095-44-5 99.23%
    Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities.
    Girinimbine
  • HY-N9508
    Perilla ketone 553-84-4 99.9%
    Perilla ketone is a naturally occurring xenobiotic compound. Perilla ketone is activated by pulmonary P450 cytochrome enzymes in the lung, resulting in severe pulmonary damage and development of diffuse pulmonary edema.
    Perilla ketone
  • HY-N9610
    Coenzyme Q6 1065-31-2 ≥99.0%
    Coenzyme Q6 (Ubiquinone 30) is an isoprenylated benzoquinone lipid. Coenzyme Q6 exhibits functions in respiratory electron transport and as a lipid antioxidant. Coenzyme Q6 also has antioxidant effects, which can prevent the production of free radicals and oxidative damage.
    Coenzyme Q6
  • HY-N9834
    Aureusidin 38216-54-5
    Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects.
    Aureusidin
  • HY-N9854
    Icariside E4 126253-42-7 98.13%
    Icariside E4 is an antinociceptive agent, and can be isolated from Tabebuia roseo-alba. Icariside E4 has peripheral analgesic activity by ATP-sensitive K+ channel-dependent mechanisms. Icariside E4 also has anti-oxidant, anti-Alzheimer and anti-inflammatory effects.
    Icariside E4
  • HY-N9895
    3,5-Dicaffeoyl-epi-quinic acid 879305-14-3
    3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC50s of 5.6 and 2.9 μg/mL respectively.
    3,5-Dicaffeoyl-epi-quinic acid
  • HY-N9921
    Antcin A 163597-24-8 99.71%
    Antcin A is a potent NLRP3 inhibitor that inhibits the assembly and activation of the NLRP3 inflammasome. Antcin A can inhibit Kupffer cell pyroptosis and has liver protective activity. Antcin A can be used to study inflammation, such as non-alcoholic fatty liver disease.
    Antcin A
  • HY-N9971
    Hentriacontane 630-04-6 98.0%
    Hentriacontane is a long-chain alkane. Hentriacontane exerts anti-inflammatory effects by inhibiting the NF-κB pathway. Hentriacontane has anti-inflammatory, antitumor and antibacterial activities.
    Hentriacontane
  • HY-NP103
    Highly purified Type III collagen, from bovine skin
    Highly purified Type III collagen, from bovine skin (Bovine Type III collagen, immunization grade) is an immune grade collagen derived from bovine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs.
    Highly purified Type III collagen, from bovine skin
  • HY-NP126
    Highly purified Type XI collagen, from porcine articular cartilage
    Highly purified Type XI collagen, from porcine articular cartilage (Porcine Type XI collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs.
    Highly purified Type XI collagen, from porcine articular cartilage
  • HY-NP134
    Flagellin from S. typhimurium
    Flagellin from S. typhimurium is a potent TLR5 agonist. Flagellin from S. typhimurium activates immune cells and inhibits the activity of melanoma cells. Flagellin from S. typhimurium activates the NF-κB pathway dependent on the TLR5/MyD88/TRAF6 signaling axis in cells. Flagellin from S. typhimurium induces a proinflammatory response in the primary chicken hepatocyte-nonparenchymal cell co-culture system by promoting IL-8 production, inhibiting IL-10 production, and increasing the IFN-γ/IL-10 ratio. Flagellin from S. typhimurium can be used for research on melanoma and inflammatory diseases.
    Flagellin from S. typhimurium
  • HY-NP143
    Nerve Growth Factor 2.5S,murine submaxillary gland 93928-24-6 98%
    Nerve Growth Factor 2.5S,murine submaxillary gland is a neurotrophic polypeptide and protein growth factor isolated from murine submaxillary glands. Nerve Growth Factor 2.5S,murine submaxillary gland increases the survival rate, phagocytic capacity and superoxide anion production level of mouse cells. Nerve Growth Factor 2.5S,murine submaxillary gland acts through cell membrane surface receptors to mediate the differentiation and maintenance of adrenergic neurons in the sympathetic nervous system. Nerve Growth Factor 2.5S,murine submaxillary gland loses its activity and undergoes dimer dissociation due to oxidation; it remains active after modification of specific tryptophan residues, while its tyrosine residues are not essential for activity. Nerve Growth Factor 2.5S,murine submaxillary gland may play a role in the inflammatory process.
    Nerve Growth Factor 2.5S,murine submaxillary gland
  • HY-NP194
    Cyclosporin A-BSA 98%
    Cyclosporin A-BSA is a conjugate of Cyclosporin A (HY-B0579) and BSA, primarily used as an immunogen to generate antibodies against Cyclosporin A for therapeutic drug monitoring and research assays.
    Cyclosporin A-BSA
  • HY-P0001
    Thymus factor X 78310-77-7 98.0%
    Thymic factor X (TFX-Jelfa) is an aqueous extract from juvenile calf thymuses and a natural stimulator of lymphocyte function.
    Thymus factor X
  • HY-P0085
    Splenopentin diacetate 105184-37-0 98.89%
    Splenopentin diacetate is a synthetic immunomodulating pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin. Splenopentin diacetate influences both early T and B cell differentiation, to increase the number of antibody-forming cells in mice after gamma irradiation.
    Splenopentin diacetate
  • HY-P0262
    Galantide 138579-66-5 98%
    Galantide, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide appears to bind to a single population of SP receptors (KD~40 nM).
    Galantide
  • HY-P0287
    QL9 159646-83-0 98%
    QL9 (QLSPFPFDL) is a high-affinity alloantigen for the 2C T cell receptor (TCR).
    QL9
  • HY-P0298
    [Des-Arg9]-Bradykinin 15958-92-6 98%
    [Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
    [Des-Arg9]-Bradykinin
Cat. No. Product Name / Synonyms Application Reactivity