2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105520
    ORG-20241 145261-31-0 98%
    ORG-20241 is a PDE3/PDE4 dual inhibitor. ORG-20241 has a significant bronchodilator effect and completely prevents allergen induced airway hyperresponsiveness. ORG-20241 can significantly inhibit eosinophil infiltration at high concentrations. ORG-20241 can be used for research on asthma.
    ORG-20241
  • HY-105524
    Lirexapride 145414-12-6 98%
    Lirexapride is a 5-HT4/Dopamine D2 receptor agonist. Lirexapride stimulants gastrointestinal motor. Lirexapride can be used for research on digestive system disorders.
    Lirexapride
  • HY-105535
    Etintidine hydrochloride 71807-56-2 98%
    Etintidine (BL-5641) hydrochloride is a potent orally active histamine H2-receptor antagonist. Etintidine hydrochloride can be used for gastrointestinal ulcer diseases research.
    Etintidine hydrochloride
  • HY-105579
    Isonixin 57021-61-1 98%
    Isonixin (Isonixine) is a non-steroidal compound. Isonixin can be used for the research of pain and inflammation.
    Isonixin
  • HY-105592
    Phenopyrazone 3426-01-5 98%
    Phenopyrazone (Diphenox), a derivative of Antipyrine (HY-B0171), exhibits oral activity as well as analgesic, antipyretic, anti-inflammatory, and antidiarrheal properties. Phenopyrazone can be used in research related to headache, rheumatism, chronic diarrhea and varicose veins.
    Phenopyrazone
  • HY-105594
    Nivimedone 49561-92-4 98%
    Nivimedone (BRL 10833 free base) is an orally active antiallergic agent. Nivimedone inhibits IgE-mediated passive cutaneous anaphylaxis in rats. Nivimedone suppresses antigen-induced histamine release from lung tissues passively sensitized with atopic serum. Nivimedone can be used in research related to bronchial asthma.
    Nivimedone
  • HY-105628
    Prodilidine 3734-17-6 98%
    Prodilidine (CI-427) is an orally active, pyrrolidine-derived non-narcotic pain inhibitor. Prodilidine exerts analgesic activity against various nociceptive stimuli, and shows no antipyretic, anti-inflammatory or respiratory depressive effects. Prodilidine fails to inhibit withdrawal symptoms of addictive agents in monkeys, but exhibits excitatory effects and enhances the crossed extensor reflex at toxic doses. Prodilidine is well absorbed from the gastrointestinal tract and metabolized via hepatic microsomal N-demethylation, displaying isomer-specific activity, toxicity and metabolic characteristics. Prodilidine can be used in research related to chronic pain (e.g., cancer-, musculoskeletal/arthritis-derived), traumatic pain and arthritic pain.
    Prodilidine
  • HY-105630
    Pipebuzone 27315-91-9 98%
    Pipebuzone (LD 4644) is an anti-inflammatory, antipyretic and analgesic agent. Pipebuzone plays an important raol in rheumatic diseases.
    Pipebuzone
  • HY-105641
    Morazone 6536-18-1 98%
    Morazone is a non-steroidal anti-inflammatory drug (NSAID).
    Morazone
  • HY-105667
    Butanixin 55285-35-3 98%
    Butanixin (2-[(4-Butylphenyl)amino]-3-pyridinecarboxylic acid) is a cyclooxygenase (COX) inhibitor. It exerts anti-inflammatory and analgesic activity by reducing prostaglandin production. It is used in the research of musculoskeletal disorders.
    Butanixin
  • HY-105671
    Balazipone 137109-71-8 98%
    Balazipone is a phenylmethylene-2,4-pentanedione compound with anti-inflammation activity. Balazipone can be used for digestive system diseases research, such as Crohn's disease.
    Balazipone
  • HY-105690
    SAR-115740 1253734-75-6 98%
    SAR-115740 is a TRPV1 antagonist. SAR-115740 exhibits developmental toxicity in H9 cell experiments. SAR-115740 can be used for research on inflammatory conditions or neurological disorders.
    SAR-115740
  • HY-105698
    Clofexamide 1223-36-5 98%
    Clofexamide (ANP 246) is an orally active antidepressant agent, exhibiting analgesic and anti-inflammatory activity. Clofexamide can be used for the research of depression, inflammatory disorders, peptic ulcer.
    Clofexamide
  • HY-105711
    RBx-7796 sodium 794528-96-4 98%
    RBx-7796 sodium is a competitive, highly selective, orally active 5-LO (IC50 = 3.5 mM for human 5-LO enzyme) inhibitor. RBx-7796 sodium can effectively inhibit 5-LO activity and LTB4 release. RBx-7796 sodium can significantly inhibit airway inflammation and bronchial constriction.
    RBx-7796 sodium
  • HY-105712
    CGP 57698 168082-74-4 98%
    CGP 57698 is an efficient CysLT receptor (Ki = 5.7 nM) antagonist. CGP 57698 can effectively counteract bronchoconstriction caused by LTD4. CGP 57698 can be used for research on asthma or allergic conditions.
    CGP 57698
  • HY-105825
    Sermetacin 57645-05-3 98%
    Sermetacin (SH-G 318AB) is an anti-inflammatory agent with biocompatibility and anti-inflammatory activity. Sermetacin is stable in saline and suitable for compound delivery. Sermetacin exhibits good biocompatibility in the RAW 264.7 mouse macrophage cell line. The anti-inflammatory response of sermetacin is comparable to that of its parent compound, indomethacin. Sermetacin may show potential in future applications of self-delivery of compound delivery.
    Sermetacin
  • HY-105852
    Proxazole 5696-09-3 98%
    Proxazole (Propoxaline) is an anti-inflammatory agent. Proxazole prevents Indomethacin (HY-14397)-induced ulcers without anti-secretory effect. Proxazole is also a spasmolytic papaverine-like agent.
    Proxazole
  • HY-105874
    Tomoxiprole 76145-76-1 98%
    Tomoxiprole (MDL 035) is a new analgesic antiinflammatory agent. Tomoxiprole selectively inhibits cyclooxygenase-2 (IC50 = 7 nM) .
    Tomoxiprole
  • HY-105885
    Sumacetamol 69217-67-0 98%
    Sumacetamol (SUR 2647) is the N-acetyl-DL-methionine ester of Paracetamol (HY-66005). Sumacetamol is orally active. Sumacetamol enhances the hepatic GSH synthesizing capacity in Bom:NMRI mice after experimental overdosage and offers protection of hepatic cell integrity, when combined with Paracetamol .
    Sumacetamol
  • HY-105933
    L-652343 107008-29-7 98%
    L-652343 is a dual cyclooxygenase/lipoxygenase inhibitor. L-652343 can inhibit the production of LTB4 in isolated human polymorphonuclear leukocytes treated with Calcimycin (HY-N6687) (IC50: 1.4 μM), but it is inactive in whole blood. L-652343 can be used in the research of inflammatory and immune diseases.
    L-652343
Cat. No. Product Name / Synonyms Application Reactivity