Tomoxiprole
Tomoxiprole (MDL 035) is a new analgesic antiinflammatory agent. Tomoxiprole selectively inhibits cyclooxygenase-2 (IC50 = 7 nM) .
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- CAS. Nr.: 76145-76-1
- Formel: C21H20N2O
- Molecular Weight:316.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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COX-2 7 nM (IC50) |
COX-1 240 nM (IC50) |
Chemical Information
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CAS. Nr. 76145-76-1
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Molecular Weight 316.40
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Formel C21H20N2O
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SMILES
CC(N1C2=CC=C(C=CC=C3)C3=C2N=C1C4=CC=C(OC)C=C4)C
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Synonyms
MDL 035
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Assandri A, et al. Pharmacokinetics and metabolism of tomoxiprole, a new analgesic antiinflammatory agent, in the rat. Eur J Drug Metab Pharmacokinet. 1985 Apr-Jun;10(2):161-70. [Content Brief]
[2]. West RE Jr, et al. Tomoxiprole selectively inhibits cyclooxygenase-2. Prostaglandins. 1997 Dec;54(6):891-8. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)