76145-76-1
76145-76-1
Chemical Structure
Tomoxiprole
Synonym(s): MDL 035
- CAS No.: 76145-76-1
- Formula:C21H20N2O
- Molecular Weight:316.40
IUPAC Name: 3-isopropyl-2-(4-methoxyphenyl)-3H-naphtho[1,2-d]imidazole
InChIKey: XVDXNSRMHBAVAX-UHFFFAOYSA-N
SMILES: CC(N1C2=CC=C(C=CC=C3)C3=C2N=C1C4=CC=C(OC)C=C4)C
Biological Activity: Tomoxiprole (MDL 035) is a new analgesic antiinflammatory agent. Tomoxiprole selectively inhibits cyclooxygenase-2 (IC50 = 7 nM) [1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tomoxiprole | Tomoxiprole (MDL 035) is a new analgesic antiinflammatory agent. Tomoxiprole selectively inhibits cyclooxygenase-2 (IC50 = 7 nM) . | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Assandri A, et al. Pharmacokinetics and metabolism of tomoxiprole, a new analgesic antiinflammatory agent, in the rat. Eur J Drug Metab Pharmacokinet. 1985 Apr-Jun;10(2):161-70. [Content Brief]
- [2]. West RE Jr, et al. Tomoxiprole selectively inhibits cyclooxygenase-2. Prostaglandins. 1997 Dec;54(6):891-8. [Content Brief]
Keywords
