2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-130757
    Remisporine B 571194-06-4 98%
    Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL.
    Remisporine B
  • HY-130787
    Apterin 53947-89-0 98%
    Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC50 value of 41.8 μM.
    Apterin
  • HY-131152
    Leucinostatin (mixture of A&B) 98%
    Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics.
    Leucinostatin (mixture of A&B)
  • HY-131396
    α-Hydroxy Montelukast 2045402-27-3 98%
    α-Hydroxy Montelukast (M7) is a metabolite of Montelukast (HY-13315A).
    α-Hydroxy Montelukast
  • HY-131411
    Naproxen methyl ester 26159-35-3 98%
    Naproxen methyl ester is a prodrug of Naproxen (HY-15030) and an ester derivative. Naproxen methyl ester is promising for research of arthritis and other inflammatory conditions1.
    Naproxen methyl ester
  • HY-131461
    6-TET Dipivaloate 314734-87-7 98%
    6-TET Dipivaloate is a nucleic acid sequencing probe.
    6-TET Dipivaloate
  • HY-131663
    L-Lysinamide 32388-19-5 98%
    L-Lysinamide is an amide form of L-Lysine (HY-N0469). L-Lysinamide can be conjugated with Cholesterol (HY-N0322) and L-ornithinamide for use as a DNA delivery agent.
    L-Lysinamide
  • HY-131728
    GPR35 agonist 3 123021-85-2 98.32%
    GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system.
    GPR35 agonist 3
  • HY-131920
    Poly(U) 27416-86-0 98%
    Poly (U) (Polyuridylic acid) is an RNA chain that exists in a disordered extended state at room temperature and serves as a TLR7 ligand. Poly (U) produces distinguishable blocking effects when transported through α-hemolysin nanopores. Poly (U) forms a triple helix with adenosine or adenosine monophosphate, thereby significantly promoting the nucleotide bond condensation reaction between adenosine monophosphate and adenosine, while exerting minimal effects on other nucleosides. When conjugated with cationic lipids, Poly (U) specifically stimulates plasmacytoid dendritic cells to produce type I interferons.
    Poly(U)
  • HY-13213A
    AM211 sodium 1263077-74-2 98%
    AM211 sodium is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
    AM211 sodium
  • HY-13219R
    Tepoxalin (Standard) 103475-41-8 98%
    Tepoxalin (Standard) is the analytical standard of Tepoxalin. This product is intended for research and analytical applications. Tepoxalin is a dual inhibitor of COX and 5-lipoxygenase (5-LO) with potent anti-inflammatory activity and a favorable gastrointestinal profile.
    Tepoxalin (Standard)
  • HY-132223
    LH1306 2182653-84-3 98%
    LH1306 is a C2-symmetric inhibitor of PD-1/PD-L1 protein-protein interaction (PPI), with an IC50 value of 25 nM. LH1306 can be used in anti-tumor research.
    LH1306
  • HY-132243
    NFAT Inhibitor-3 841210-82-0 98%
    NFAT Inhibitor-3 (Compound 10) is a factor nuclear factor of activated T cells (NFAT) inhibitor. NFAT Inhibitor-3 inhibits IL-2 production. NFAT Inhibitor-3 binds in a sequence-selective manner directly to DNA. NFAT Inhibitor-3 can be used for the research of transcription factor dysregulation.
    NFAT Inhibitor-3
  • HY-132289
    Lipid M 2089251-57-8 98%
    Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability.
    Lipid M
  • HY-13262R
    Lumacaftor (Standard) 936727-05-8 98%
    Lumacaftor (Standard) is the analytical standard of Lumacaftor. This product is intended for research and analytical applications. Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.
    Lumacaftor (Standard)
  • HY-13269R
    BMS-707035 (Standard) 729607-74-3 98%
    BMS-707035 (Standard) is the analytical standard of BMS-707035. This product is intended for research and analytical applications. BMS-707035 is a potent orally active HIV-1 integrase strand transfer inhibitor (INSTI). BMS-707035 has enzyme inhibitory with an IC50 value of 3 nM. BMS-707035 also has weak CYP inhibiton and antiviral activity. BMS-707035 can be used for the research of human immunodeficiency virus-1 (HIV-1).
    BMS-707035 (Standard)
  • HY-133003
    L662,025 122328-38-5 98%
    L662,025 is a specific, photolabile and irreversible Platelet-activating factor (PAF-receptor) antagonist, with IC50 values of 5.6 μM (platelet aggregation) and 1 μM (receptor binding), respectively.
    L662,025
  • HY-133215
    Zileuton sulfoxide 1147524-83-1 98%
    Zileuton sulfoxide is a sulfoxide derivative of Zileuton (HY-14164), a potent and selective inhibitor of lipoxygenase 5-LOX with anti-asthmatic properties.
    Zileuton sulfoxide
  • HY-13344R
    PF-8380 (Standard) 1144035-53-9 98%
    PF-8380 (Standard) is the analytical standard of PF-8380. This product is intended for research and analytical applications. PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood.
    PF-8380 (Standard)
  • HY-133672
    (Rac)-Mono(3,5,5-trimethylhexyl) phthalate 297182-83-3 98%
    (Rac)-Mono(3,5,5-trimethylhexyl) phthalate is a important metabolite of commonly used phthalate plasticizers. (Rac)-Mono(3,5,5-trimethylhexyl) phthalate has immuno-suppressive effect.
    (Rac)-Mono(3,5,5-trimethylhexyl) phthalate
Cat. No. Product Name / Synonyms Application Reactivity