Lumacaftor (Standard)
Lumacaftor (Standard) is the analytical standard of Lumacaftor. This product is intended for research and analytical applications. Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98%
- CAS No.: 936727-05-8
- Formule: C24H18F2N2O5
- Masse moléculaire:452.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-13262
LumacaftorCFTR Modulator -
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GlyH-101CFTR Inhibitor -
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GLPG1837 -
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PPQ-102CFTR Inhibitor -
HY-14832R
Ataluren (Standard)CFTR Inhibitor -
HY-15448R
Tezacaftor (Standard)CFTR Corrector
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 936727-05-8
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Masse moléculaire 452.41
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Formule C24H18F2N2O5
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SMILES
FC1(F)OC(C=C(C=C2)C3(CC3)C(NC4=NC(C5=CC=CC(C(O)=O)=C5)=C(C=C4)C)=O)=C2O1
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Synonyms
VX-809 (Standard); VRT 826809 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Van Goor F, et al. Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18843-8. [Content Brief]
[2]. Phuan PW, et al. Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy. Mol Pharmacol. 2014 Jul;86(1):42-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lumacaftor (Standard) Related Classifications
HY-13262R Related Classifications
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