2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Nombre del producto No. CAS Pureza Estructura química
  • HY-P991255
    VRDN-002 98%
    VRDN-002 is a human monoclonal antibody (mAb) targeting IGF1R/CD221. VRDN-002 reduces inflammation and proptosis in thyroid eye disease (TED). VPI-2690B can be used in Graves ophthalmopathy research.
    VRDN-002
  • HY-P991288
    OPR-003 98%
    OPR-003 is a human monoclonal antibody targeting IL-6. OPR-003 can be used in the research of Haematological malignancies and Rheumatoid arthritis.
    OPR-003
  • HY-P991313
    PD-360324 98%
    PD-360324 is a human monoclonal antibody (mAb) targeting CSF1/M-CSF. PD-360324 can be used in cutaneous lupus erythematosus, pulmonary sarcoidosis and rheumatoid arthritis research.
    PD-360324
  • HY-P991341
    FF-21101
    FF-21101 is a human IgG1 monoclonal antibody (mAb) targeting CDH3/P-cadherin. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    FF-21101
  • HY-P991477
    HFB-100204 98%
    HFB-100204 is a human monoclonal antibody (mAb) targeting CXCR5. HFB-100204 reduces CXCR5+ immune cells, including B cells and Tfh cells, in the blood and spleen of hCXCR5 knockout mice. HFB-100204 can be used in autoimmune diseases research.
    HFB-100204
  • HY-P991502
    Armenian hamster IgG1 kappa, Isotype Control 98%
    Armenian hamster IgG1 kappa, Isotype Control, a Armenian hamster monoclonal antibody, is an isotype control for Armenian hamster IgG1 kappa antibody.
    Armenian hamster IgG1 kappa, Isotype Control
  • HY-P991532
    AT002 98%
    AT002 (CBAS-173, EJ212/007-Cl2-5) is a recombinant human IgG1 monoclonal antibody. AT002 targets the cell surface protein activated leukocyte adhesion molecule (ALCAM)/CD166. AT002 can be used in the research of cancer, autoimmune diseases and inflammatory diseases.
    AT002
  • HY-P991543
    BTI-322 339181-10-1 98.15%
    BTI-322 is a human IgG1κ antibody directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90% of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease.
    BTI-322
  • HY-P991629
    C1 Esterase Inhibitor (Human)
    C1 Esterase Inhibitor (Human) is a C1 Esterase inhibitor derived from human plasma. C1 Esterase Inhibitor (Human), a glycoprotein, is a serum protease inhibitor (serpin) that binds covalently and inactivates C1r, C1s, and mannan-binding protein-associated proteases (MASPs). C1 Esterase Inhibitor (Human) has anti-inflammatory effects. C1 Esterase Inhibitor (Human) can be used to prevent angioedema attacks associated with hereditary angioedema.
    C1 Esterase Inhibitor (Human)
  • HY-P991651
    MEDI4212 98%
    MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. MEDI4212 potently inhibits human IgE-mediated functional responses through its receptor FcεRI, such as calcium signaling, β-hexosaminidase release and phagocytosis. MEDI4212 prevents the binding of IgE to CD23 with an IC50 of 8 nM. MEDI4212 can be used severe asthma research.
    MEDI4212
  • HY-P991745
    Anti-Mouse CCR2 Antibody (C2Mab-6) 98%
    Anti-Mouse CCR2 Antibody (C2Mab-6) is raised against and binds to the N-terminal sequence of CCR2. Recommend Isotype Controls: Rat IgG1 kappa, Isotype Control (HY-P99979).
    Anti-Mouse CCR2 Antibody (C2Mab-6)
  • HY-P991775
    Anti-Rat CTLA-4 Antibody (WKH203) 98%
    Anti-Rat CTLA-4 Antibody (WKH203) reacts with rat CTLA-4. Anti-Rat CTLA-4 Antibody (WKH203) binds to the CTLA-4 protein disrupts the key signaling mechanisms linked to the suppression of T cell activity, triggering T cells readily and enhancing the immune system’s capacity to identify and eliminate cancer. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-Rat CTLA-4 Antibody (WKH203)
  • HY-P991787
    Anti-HLA-A2 Antibody (BB7.2) 98%
    Anti-HLA-A2 Antibody (BB7.2) reacts with the alpha subunit of the human leukocyte antigen-A2 (HLA-A2). Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982).
    Anti-HLA-A2 Antibody (BB7.2)
  • HY-P991806
    Anti-Mouse MHC Class I (H-2Kb) Antibody (AF6-88.5) 98%
    Anti-Mouse MHC Class I (H-2Kb) Antibody (AF6-88.5) reacts with the mouse H-2Kb MHC class I alloantigen. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).
    Anti-Mouse MHC Class I (H-2Kb) Antibody (AF6-88.5)
  • HY-P991815
    Anti-Mouse CD90.1 Antibody (OX-7) 98%
    Anti-Mouse CD90.1 Antibody (OX-7) reacts with the mouse and rat CD90.1. CD90 is present on a variety of cell types in murine and rat, including lymphatic vessels, T cells, neurons and fibroblasts. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-Mouse CD90.1 Antibody (OX-7)
  • HY-P991816
    Mouse IgM, Isotype Control 98%
    Mouse IgM, Isotype Control, a mouse monoclonal antibody, is an isotype control for mouse IgM antibody.
    Mouse IgM, Isotype Control
  • HY-P991827
    Anti-Mouse CTLA-4 Antibody (UC10-4F10-11) 98%
    Anti-Mouse CTLA-4 Antibody (UC10-4F10-11) reacts with mouse cytotoxic T lymphocyte antigen-4 (CTLA-4, CD152). Anti-Mouse CTLA-4 Antibody (UC10-4F10-11) promotes T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding. Recommend Isotype Controls: Polyclonal Armenian hamster IgG, Isotype Control (HY-P990305).
    Anti-Mouse CTLA-4 Antibody (UC10-4F10-11)
  • HY-P991848
    Anti-CD64 Antibody (10.1) 98%
    Anti-CD64 Antibody (10.1) recognizes an epitope on human CD64 (Fc_RI). Fc gamma receptors (Fc_Rs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-CD64 Antibody (10.1)
  • HY-P991893
    Anti-CD5 Antibody (MAT 304) 98%
    Anti-CD5 Antibody (MAT 304) is an antibody against human CD5.
    Anti-CD5 Antibody (MAT 304)
  • HY-P991931
    Anti-CD72 Antibody 98%
    Anti-CD72 Antibody is an antibody against human CD72. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CD72 Antibody
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