2. Metabolic Disease

Metabolic Disease (代謝)

Metabolic Disease

関連製品

PDF 53.7 MB

Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-P3185
    beta-Galactose dehydrogenase 9028-54-0
    beta-Galactose dehydrogenase can make conversion of galactose to galactonolactone and the concomitant reduction of NAD to the fluorescent NADH. beta-Galactose dehydrogenase can be used for the determination of galactose.
    beta-Galactose dehydrogenase
  • HY-P3213
    Dp[Tyr(methyl)2,Arg8]-Vasopressin 67269-08-3
    Dp[Tyr(methyl)2,Arg8]-Vasopressin is a non-selective peptide arginine vasopressin Vlb receptor antagonist.
    Dp[Tyr(methyl)2,Arg8]-Vasopressin
  • HY-P3278
    Caloxin 2A1 350670-85-8
    Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase.
    Caloxin 2A1
  • HY-P3314
    Nendratareotide 2251119-65-8
    Nendratareotide is a somatostatin analogue.
    Nendratareotide
  • HY-P3341
    OB3 259535-56-3
    OB3, a derivative of Leptin, show more effective than leptin in reducing obesity and diabetes in mouse models. OB3 can reduce Leptin-related inflammation and proliferation in hepatocellular carcinoma cells.
    OB3
  • HY-P3388
    Utreglutide 2460862-12-6 98.42%
    Utreglutide is a potent glucagon-like peptide 1 (GLP-1) receptor agonit.
    Utreglutide
  • HY-P3413
    H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH 683750-83-6
    H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EM7) is a mesenchymal stem cells (MSC)-specific peptide.
    H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH
  • HY-P3444
    CD31 161374-99-8
    CD31 (PECAM-1) is platelet endothelial cell adhesion molecule-1, serves as the endothelial cell-specific receptor of clostridium perfringens b-Toxin (CPB). CD31 is also an ER-MP12 antigen, acts as a linker between mechanical stress, metabolism and inflammation. CD31 peptide is able to sustain phosphorylation of the CD31 ITIM686 and of SHP2 and to inhibit TCR-induced T-cell activation-.
    CD31
  • HY-P3491
    Pegloxenatide 2420483-82-3
    Pegloxenatide is a glucagon-like peptide-1 receptor (GLP-1 RA) agonist. Pegloxenatide can be used for type 2 diabetes research.
    Pegloxenatide
  • HY-P3507
    Dalazatide 1081110-69-1
    Dalazatide (ShK-186) is a specific Kv1.3 potassium channel peptide inhibitor. Dalazatide can be used in the study of autoimmune diseases such as multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes and inflammatory bowel disease.
    Dalazatide
  • HY-P3542
    Des His1, Glu8 Exendin-4
    Des His1, Glu8 Exendin-4 is a potent glucagon-like peptide-1 receptor (GLP-1-R) antagonist. Des His1, Glu8 Exendin-4 improves glucose homeostasis by regulating both insulin secretion and glucose production. Des His1, Glu8 Exendin-4 can be used for the research of type 2 diabetic and gastrointestinal.
    Des His1, Glu8 Exendin-4
  • HY-P3568
    Adipokinetic hormone (Gryllus bimaculatus) 113800-65-0
    Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans.
    Adipokinetic hormone (Gryllus bimaculatus)
  • HY-P3570
    Adipokinetic hormone II (Locusta migratoria) 98968-94-6
    Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs).
    Adipokinetic hormone II (Locusta migratoria)
  • HY-P3577
    [Tyr0] Gastric Inhibitory Peptide (23-42), human 121765-67-1
    [Tyr0] Gastric Inhibitory Peptide (23-42), human, a glucose-dependent insulinotropic polypeptide (GIP), is a weak inhibitor of gastric acid secretion that also stimulates insulin secretion. [Tyr0] Gastric Inhibitory Peptide (23-42), human can be used in diabetes, obesity research.
    [Tyr0] Gastric Inhibitory Peptide (23-42), human
  • HY-P3580
    Acetyl Gastric Inhibitory Peptide (human) 299898-33-2
    Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity.
    Acetyl Gastric Inhibitory Peptide (human)
  • HY-P3608
    [Des-His1,Glu9] Glucagon 110121-11-4
    [Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes.
    [Des-His1,Glu9] Glucagon
  • HY-P3611
    Valosin (porcine) 99510-37-9
    Valosin (porcine) is a biologically active peptide with 25-amino-acid. Valosin (porcine) can be isolated recently from pig intestine. Valosin (porcine) can be used for the research of digestive system.
    Valosin (porcine)
  • HY-P3616
    Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
    Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin.
    Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
  • HY-P3617
    Glucagon (22-29) 32204-93-6
    Glucagon (22-29) is partial agonist of Glucagon (19–29). Glucagon specifically inhibits the Ca2+ pump in liver plasma membranes independently of adenylate cyclase activation.
    Glucagon (22-29)
  • HY-P3621
    Biotinyl-Glucagon (1-29), human, bovine, porcine
    Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream.
    Biotinyl-Glucagon (1-29), human, bovine, porcine
製品番号 製品名 / Synonyms Application Reactivity