Adipokinetic hormone (Gryllus bimaculatus) (Synonyms: Grybi-AKH)

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Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans.

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Adipokinetic hormone (Gryllus bimaculatus) Chemical Structure

CAS No. : 113800-65-0

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Description

In Vivo

Adipokinetic hormone Gryllus bimaculatus (100 pmol/per; topical application; single) stimulates locomotory activity via the increase of haemolymph lipid titres^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	3-day-old adult female Gryllus bimaculatus (Ensifera, Gryllidae)^[1].
Dosage:	100 pmol/per
Administration:	Topical application onto the surface of the dorsal thorax under the wings
Result:	Resulted in a rapid increase in haemolymph lipid titres.

Molecular Weight

919.98

Formula

C₄₃H₅₇N₁₁O₁₂

CAS No.

113800-65-0

Sequence Shortening

{Glp}-VNFSTGW-NH2

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lorenz M W, et al. Lipid mobilization and locomotor stimulation in Gryllus bimaculatus by topically applied adipokinetic hormone[J]. Physiological Entomology, 2004, 29(2): 146-151.

[2]. Zhou YJ, et al. Effects of adipokinetic hormone and its related peptide on maintaining hemolymph carbohydrate and lipid levels in the two-spotted cricket, Gryllus bimaculatus. Biosci Biotechnol Biochem. 2018 Feb;82(2):274-284. [Content Brief]

[3]. Bernice Z. Schacter, et al. Compositions and methods for promoting lipid mobilization, glycogen mobilization, or both, in humans. Patent WO2003066080A1.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adipokinetic hormone (Gryllus bimaculatus)113800-65-0Grybi-AKHOtherstwo-spotted cricketglycogen storage disordersobesitylocomotorInhibitorinhibitorinhibit

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