113800-65-0
Chemical Structure
Adipokinetic hormone (Gryllus bimaculatus)
Synonym(s): Grybi-AKH
- CAS No.: 113800-65-0
- Formula:C43H57N11O12
- Molecular Weight:919.98
InChIKey: ZEFDDGDBQYNXBK-OCVFHUKVSA-N
SMILES: O=C([C@@H]1CCC(N1)=O)N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(NCC(N[C@H](C(N)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O
Biological Activity: Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans[1][2][3].
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Adipokinetic hormone (Gryllus bimaculatus) | Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans. | |||||||||||||||||||||
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References
- [1]. Lorenz M W, et al. Lipid mobilization and locomotor stimulation in Gryllus bimaculatus by topically applied adipokinetic hormone[J]. Physiological Entomology, 2004, 29(2): 146-151.
- [2]. Zhou YJ, et al. Effects of adipokinetic hormone and its related peptide on maintaining hemolymph carbohydrate and lipid levels in the two-spotted cricket, Gryllus bimaculatus. Biosci Biotechnol Biochem. 2018 Feb;82(2):274-284. [Content Brief]
- [3]. Bernice Z. Schacter, et al. Compositions and methods for promoting lipid mobilization, glycogen mobilization, or both, in humans. Patent WO2003066080A1.
