1. Membrane Transporter/Ion Channel
  2. Proton Pump
  3. Caloxin 2A1

Caloxin 2A1 

Cat. No.: HY-P3278
Handling Instructions

Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Caloxin 2A1 Chemical Structure

Caloxin 2A1 Chemical Structure

CAS No. : 350670-85-8

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Description

Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].

In Vitro

Caloxin 2A1 inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate[1].
Caloxin 2A1 increases airway smooth muscle cells (ASMCs) apoptosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1478.52

Formula

C₆₄H₉₁N₁₉O₂₂

CAS No.
Sequence Shortening

VSNSNWPSFPSSGGG-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Caloxin 2A1
Cat. No.:
HY-P3278
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