1. Membrane Transporter/Ion Channel
  2. Proton Pump
  3. Caloxin 2A1 TFA

Caloxin 2A1 TFA 

Cat. No.: HY-P3278A
Handling Instructions

Caloxin 2A1 TFA is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 TFA does not affect basal Mg2+-ATPase or Na+-K+-ATPase.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Caloxin 2A1 TFA Chemical Structure

Caloxin 2A1 TFA Chemical Structure

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Description

Caloxin 2A1 TFA is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 TFA does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].

In Vitro

Caloxin 2A1 TFA inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 TFA also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate[1].
Caloxin 2A1 TFA increases airway smooth muscle cells (ASMCs) apoptosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1592.54

Formula

C₆₆H₉₂F₃N₁₉O₂₄

Sequence Shortening

VSNSNWPSFPSSGGG-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Caloxin 2A1 TFA
Cat. No.:
HY-P3278A
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