2. Metabolic Disease

Metabolic Disease

Metabolic Disease

Related Products

PDF 53.7 MB

Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-N2475
    Lappaol A 62333-08-8 98.63%
    Lappaol A is a natural compound with antiaging activity.
    Lappaol A
  • HY-N2608
    7-O-Ethylmorroniside 945721-10-8 99.91%
    7-O-Ethylmorroniside is a iridoid glucoside from the fruit of Cornus officinalis which is a traditional medicine in China and used for the reserch of kidney diseases, including diabetic nephropathy.
    7-O-Ethylmorroniside
  • HY-N2746
    7-O-Geranylscopoletin 28587-43-1
    7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia.
    7-O-Geranylscopoletin
  • HY-N2840
    Allitol 488-44-8 99.61%
    Allitol (Allodulcitol) is an orally active rare sugar alcohol found in Itea virginica L, Tylopilus plumbeoviolaceus. Allitol has anti-obesity and hypoglycaemic activities. Allitol reduces carcass and total body fat mass, increases cecal weight, surface area, and short-chain fatty acid production, and upregulates cecal microbial enzymes linked to butyrate metabolism. Allitol can be used for the researches of obesity and diabetes.
    Allitol
  • HY-N2868
    Andropanoside 82209-72-1 99.57%
    Andropanoside is a natural product and possesses a protective activity against various liver disorders.
    Andropanoside
  • HY-N2948
    Boeravinone E 137787-00-9 99.73%
    Boeravinone E exhibits spasmolytic activity.
    Boeravinone E
  • HY-N2998
    Ganoderenic acid A 100665-40-5
    Ganoderenic acid A is a lanostane-type triterpene. Ganoderenic acid A is a potent inhibitor of β-glucuronidase. Ganoderenic acid A has a potent hepatoprotective effect against CCl4-induced liver injury.
    Ganoderenic acid A
  • HY-N3027
    Soyasaponin Aa 117230-33-8
    Soyasaponin Aa is a soyasaponin that can be found in soy. Soyasaponin Aa suppresses PPARγ transcriptional activity, reduces PPARγ and C/EBPα expression, inhibits adipocyte differentiation and lipid accumulation, and reduces adipogenic marker gene expression. Soyasaponin Aa reduces hydrogen peroxide-induced reactive oxygen species (ROS) production and malondialdehyde levels. Soyasaponin Aa exhibits cellular antioxidant activity. Soyasaponin Aa can be used for the research of obesity.
    Soyasaponin Aa
  • HY-N3033
    N-​Benzyllinolenamide 883715-18-2 99.70%
    N-​Benzyllinolenamide is a natural macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH) with an IC50 of 41.8 μM.
    N-​Benzyllinolenamide
  • HY-N3085
    Phellamurin 52589-11-4
    Phellamurin is a plant flavonone glycoside from the leaves of Phellodendron amurense and inhibits intestinal P-glycoprotein. Phellamurin also inhibits egg laying by Papilio protenor. Phellamurin induces cells apoptosis and has anti-tumor activity.
    Phellamurin
  • HY-N3501
    Deacetyl Ganoderic Acid F 100665-44-9 98.82%
    Deacetyl Ganoderic Acid F is a 7-anostane triterpenoid from Ganoderma lucidum.
    Deacetyl Ganoderic Acid F
  • HY-N3628
    Coronarin A 119188-33-9 ≥98.0%
    Coronarin A is an orally active natural compound that inhibits mTORC1 and S6K1 to increase IRS1 activity. Coronarin A shows anti-inflammatory activity and can also be used for type 2 diabetes mellitus research.
    Coronarin A
  • HY-N3925
    Ganoderol A 104700-97-2
    Ganoderol A is a terpenoid extracted from Ganoderma lucidum with antimicrobial activities. Ganoderol A inhibits cholesterol synthesis pathway and has significant anti-inflammatory activity and protection against ultraviolet A (UVA) damage.
    Ganoderol A
  • HY-N3960
    Glycyrin 66056-18-6 98.0%
    Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity.
    Glycyrin
  • HY-N4019
    Maohuoside A 128988-55-6 99.47%
    Maohuoside A, a single compound isolated from the E. koreanum that potently promotes osteogenesis. Maohuoside A enhances the osteogenesis of bone marrow-derived mesenchymal stem cells via bone morphogenetic protein (BMP) and MAPK signaling pathways.
    Maohuoside A
  • HY-N4120
    Valechlorine 51771-49-4 98%
    Valechlorine, an iridoid, is an autophagy enhancer. Valechlorine is effective in alleviating fatty liver by acting as an autophagy enhancer to break down lipid droplets. Valechlorine can be used for the study of nonalcoholic fatty liver disease (NAFLD).
    Valechlorine
  • HY-N4173
    8-Oxoepiberberine 19716-60-0 99.72%
    8-Oxoepiberberine is an alkaloid metabolite in the plasma after oral administration of Zuojin formula, a traditional chinese medicine used to treat gastrointestinal disease.
    8-Oxoepiberberine
  • HY-N4179
    Aurantio-obtusin β-D-glucoside 129025-96-3 ≥99.0%
    Aurantio-obtusin β-D-glucoside (Glucoaurantio-obtusin), isolated from Cassiae Semen (seeds of Cassia tora), is a glucoside of aurantio-obtusin.
    Aurantio-obtusin β-D-glucoside
  • HY-N4200
    S-Dihydrodaidzein 879559-75-8 98%
    S-Dihydrodaidzein is the (S)-enantiomer of dihydrodaidzein which is one of the most prominent dietary phytoestrogens.
    S-Dihydrodaidzein
  • HY-N4219
    Saikosaponin B3 58316-42-0 98.10%
    Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells.
    Saikosaponin B3
Cat. No. 상품명 / Synonyms Application Reactivity