Glycyrin

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Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity.

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Glycyrin Chemical Structure

CAS No. : 66056-18-6

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Description	Glycyrin is a PPAR-γ ligand of licorice. Glycyrin can decrease the blood glucose levels of genetically diabetic mice. Glycyrin also shows antibacterial activity^[1]^[2]^[3].
Molecular Weight	382.41
Formula	C₂₂H₂₂O₆
CAS No.	66056-18-6
SMILES	O=C1C(C2=CC=C(O)C=C2O)=CC3=C(OC)C(C/C=C(C)\C)=C(OC)C=C3O1
Structure Classification	Phenylpropanoids Coumarins
Initial Source	Plants Leguminosae Glycyrrhiza uralensis Fisch.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (267 KB) Handling Instructions (2659 KB)
References	[1]. Kuroda M,et, al. Phenolics with PPAR-gamma ligand-binding activity obtained from licorice (Glycyrrhiza uralensis roots) and ameliorative effects of glycyrin on genetically diabetic KK-A(y) mice. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4267-72. [Content Brief] [2]. Tanaka Y, et, al. Antibacterial compounds of licorice against upper airway respiratory tract pathogens. J Nutr Sci Vitaminol (Tokyo). 2001 Jun;47(3):270-3. [Content Brief] [3]. Wang Q, et, al. Metabolites identification of glycyrin and glycyrol, bioactive coumarins from licorice. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 1:983-984:39-46. [Content Brief]

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycyrin66056-18-6PPARBacterialPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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Glycyrin

Glycyrin Related Antibodies

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Biological Activity

Purity & Documentation

References

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