1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. Lipoxygenase Inhibitors

Lipoxygenase Inhibitors

5-LOX

12-LOX

15-LOX

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Lipoxygenase Inhibitors, Antagonists & Modulators
Product Name 5-LOX 12-LOX 15-LOX Purity
U-73122
5-LOX
    ≥98.0%
Wedelolactone
5-LOX, IC50: 2.5 μM
    99.70%
Zileuton
5-LOX
    99.58%
Nordihydroguaiaretic acid
5-LOX, IC50: 8 μM
    99.88%
ML355  
12-LOX, IC50: 0.34 μM
  98.42%
15-LOX-1 inhibitor 1    
15-LOX-1, IC50: 0.19 μM
Caffeic acid
5-LO
    98.71%
Indirubin-3'-monoxime
5-LOX, IC50: 7.8-10 μM
    99.89%
Psoralidin
5-LOX
    99.90%
Docebenone
5-LO
    99.10%
Licofelone
5-LOX, IC50: 0.18 μM
    98.04%
Pectolinarigenin
5-LOX
    99.47%
S-(+)-Marmesin
5-LOX
    99.11%
5-O-Demethylnobiletin
5-LOX, IC50: 0.1 μM
    99.93%
PF-4191834
5-LOX
    99.77%
2,5-Di-tert-butylhydroquinone
5-LO, IC50: 1.8 μM
    ≥98.0%
11-​Keto-​beta-​boswellic acid
5-LOX
    99.60%
β-Boswellic acid
5-LO
    98.59%
Lonapalene
5-LO
    99.07%
Picrinine
5-Lipoxygenase
    99.33%
Zileuton sodium
5-Lipoxygenase
   
Enazadrem
5-Lipoxygenase
   
PGS-IN-1
5-Lipoxygenase, IC50: 1.05 μM
    99.51%
Malotilate
5-Lipoxygenase, IC50: 4.7 μM
    99.54%
Cirsiliol
5-Lipoxygenase
   
3-O-Acetyl-11-hydroxy-beta-boswellic acid
5-LOX
    98.29%
Phenethyl ferulate
5-LOX, IC50: 5.75 μM
   
Lycopodine
5-Lipoxygenase
   
ICI 211965
5-LPO
   
Atreleuton
5-LO
   
A-69412
5-LO
   
LP117
5-LO, IC50: 1.1 μM
   
LY 178002
5-LPO, IC50: 0.6 μM
   
RWJ 63556
5-Lipoxygenase
   
S-2474
5-LO
   
CMI977
5-LO
   
COX/5-LO-IN-1
5-LO, IC50: 2 μM
   
CMI-392
5-LO, IC50: 100 nM
   
AZD 4407
5-Lipoxygenase
   
5-Lipoxygenase-In-1
5-Lipoxygenase
    98.07%
Bunaprolast
5-LO