2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P4071
    OH-CATH
    		Inhibitor
    OH-CATH is a natural antimicrobial peptide that can be isolated from the venom and tissue of Ophiophagus hannah (King Cobra).
    OH-CATH
  • HY-162503
    ST166 free acid
    		Inhibitor
    ST166 free acid is a inhibitor of formation of the PhoP-DNA complex with the IC50 values of 18 and 24 μM against PhoP and MtrAC binding with DNA, respectively. ST166 free acid shows antibacterial activity against Macrobacterium marinum.
    ST166 free acid
  • HY-109706
    (Rac)-CPI-098
    		Inhibitor
    (Rac)-CPI-098 shows antibacterial activity. (Rac)-CPI-098 exhibits superior anti-fungal activity against Monascus ruber, better activity against Aspergillus fumigates, good activity against Aspergillus niger and Aspergillus parasites and moderate activity against Candida albicans.
    (Rac)-CPI-098
  • HY-P5020
    Crotalicidin
    		Inhibitor
    Crotalicidin is an antimicrobial peptide and anti-tumor peptide that can effectively inhibit the activity of Gram-negative bacteria and tumor cells. Crotalicidin can be obtained from rattlesnake venom. Crotalicidin can be used in the study of microbial infections and cancer.
    Crotalicidin
  • HY-105519
    M 14659
    		Inhibitor
    M 14659 is a potent injectable semisynthetic cephalosporin antibiotic. M 14659 has a strong inhibitory effect on Gram-negative bacteria, including Pseudomonas aeruginosa.
    M 14659
  • HY-131107
    Cefpodoxime proxetil impurity B
    		Inhibitor
    Cefpodoxime proxetil impurity B is an impurity of Cefpodoxime proxetil (HY-N7101). Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin.
    Cefpodoxime proxetil impurity B
  • HY-131554
    Tibezonium iodide
    		Inhibitor
    Tibezonium iodide, an oropharyngeal disinfectant, has antibacterial activity for the prevention of mouth infections.
    Tibezonium iodide
  • HY-132910
    Antitubercular agent-9
    		Inhibitor
    Antitubercular agent-9 shows effective antitubercular activity with a MIC value of 1.03-2.32 μM.
    Antitubercular agent-9
  • HY-P10150
    IN-2-LF
    		Inhibitor
    IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R.
    IN-2-LF
  • HY-N12230
    Penicolinate B
    		Inhibitor
    Penicolinate B is a picolinic acid derivative that can be isolated from Penicillium sp. Penicolinate B exhibits antimalarial activity (IC50: 1.40 μg/mL), antitubercular activity (MIC: 25.0 μg/mL), activity against Bacillus cereus (IC50: 25.0 μg/mL), and activity against Candida albicans (IC50: 1.45 μg/mL). Penicolinate B also has certain cytotoxicity against cancer cells such as MCF-7, KB, and NCI-H187. Penicolinate B can be used in research on malaria, tuberculosis, bacterial/fungal infections and tumors.
    Penicolinate B
  • HY-183935
    NDM-1-IN-13
    		Inhibitor
    NDM-1-IN-13 is a NDM-1 inhibitor with an IC50 of 3.27 μM. As an Antibiotic synergist, NDM-1-IN-13 synergistically reduces the minimum inhibitory concentration of Meropenem (HY-13678) against NDM-1-positive bacterial isolates. NDM-1-IN-13 can be used in studies related to NDM-1-positive bacterial infections.
    NDM-1-IN-13
  • HY-N6687B
    Calcimycin hemimagnesium
    		Inhibitor
    Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis and autophagy.
    Calcimycin hemimagnesium
  • HY-B0220B
    Erythromycin (gluceptate)
    		Inhibitor
    Erythromycin gluceptate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin gluceptate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin gluceptate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
    Erythromycin (gluceptate)
  • HY-P10693
    CZEN-002
    		Inhibitor
    CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α.
    CZEN-002
  • HY-W540874
    1-Heptadecene
    		Inhibitor
    1-Heptadecene is a metabolite found in Aporosa cardiosperma. 1-Heptadecene has antifungal and antibacterial activities.
    1-Heptadecene
  • HY-162346
    KN-17
    		Inhibitor
    KN-17 is a modified based on the structure of cecropin B (HY-P0092), can effectively interfere with bacterial growth and induce the migration of human bone marrow stromal cells (hBMSCs). KN-17 can significantly stimulate angiogenesis in vitro and in vivo.
    KN-17
  • HY-168281
    P6P-10,10
    		Inhibitor
    P6P-10,10 is an antimicrobial agent. P6P-10,10 has an IC50 value of 3 μM against colistin-resistant Acinetobacter baumannii.
    P6P-10,10
  • HY-130570
    β-Gal-NONOate
    		Inhibitor
    Beta-gal-nonoate is a β-galactosidase dependent nitric oxide (NO) donor that releases NO once activated by β-galactosidase. β-Gal-NONOate has bactericidal activity and can be used as a bactericide .
    β-Gal-NONOate
  • HY-117831
    NSC-79887
    		Inhibitor
    NSC-79887 is a nucleoside hydrolase (NH) inhibitor with activity against Bacillus anthracis. NSC-79887 is considered a good candidate inhibitor of nucleoside hydrolases for biological testing and further development. The pharmacokinetic (ADMET) prediction of NSC-79887 showed that all physicochemical parameters were within the acceptable range for human use.
    NSC-79887
  • HY-139595
    Polyketide synthase 13-IN-2
    		Inhibitor
    Polyketide synthase 13-IN-2 (comp 42) is a polyketide synthase 13 inhibitor against Mycobacterium tuberculosis, with an MIC of 0.25 μg/mL.
    Polyketide synthase 13-IN-2
Cat. No. Product Name / Synonyms Application Reactivity