Polyketide synthase 13-IN-2
Polyketide synthase 13-IN-2 (comp 42) is a polyketide synthase 13 inhibitor against Mycobacterium tuberculosis, with an MIC of 0.25 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 2219338-48-2
- Formula: C22H21NO5
- Molecular Weight:379.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>50 μg/mL
Compound: 42
|
Cytotoxicity against human HEK293 cells after 48 hrs by CellTiter96 AQueous one solution assay
Cytotoxicity against human HEK293 cells after 48 hrs by CellTiter96 AQueous one solution assay
|
[PMID: 29328655] |
| HFL1 | IC50 |
50.2 μg/mL
Compound: 42
|
Cytotoxicity against HFL1 cells after 48 hrs by CellTiter96 AQueous one solution assay
Cytotoxicity against HFL1 cells after 48 hrs by CellTiter96 AQueous one solution assay
|
[PMID: 29328655] |
| MRC5 | IC50 |
>50 μg/mL
Compound: 42
|
Cytotoxicity against human MRC5 cells after 48 hrs by CellTiter96 AQueous one solution assay
Cytotoxicity against human MRC5 cells after 48 hrs by CellTiter96 AQueous one solution assay
|
[PMID: 29328655] |
| Vero | IC50 |
4 μg/mL
Compound: 42
|
Cytotoxicity against African green monkey Vero cells after 72 hrs by MABA
Cytotoxicity against African green monkey Vero cells after 72 hrs by MABA
|
[PMID: 29328655] |
Chemical Information
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CAS No. 2219338-48-2
-
Molecular Weight 379.41
-
Formula C22H21NO5
-
SMILES
O=C1OC2=C(C3=C1C4=C(C=CC(O)=C4CN5CCCCC5)O3)C=CC(OC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)