2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

Related Products

PDF 14.26 MB

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0250R
    Saikosaponin D (Standard)
    		Inhibitor
    Saikosaponin D (Standard) is the analytical standard of Saikosaponin D. This product is intended for research and analytical applications. Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.
    Saikosaponin D (Standard)
  • HY-115939
    Urease-IN-2
    		Inhibitor
    Urease-IN-2 (compound 8g) is a non-competitive urease inhibitor with an IC50 of 0.94 μM and a Ki of 1.6 μM. Urease-IN-2 inhibits the Jack bean urease (JBU) in a non-competitive manner.
    Urease-IN-2
  • HY-W668469
    2-Methyldecalin
    		Inhibitor
    2-Methyldecalin is an active ingredient that can be extracted from Crambe cordifolia. 2-Methyldecalin has antioxidant activity, antibacterial activity, and high biological safety. 2-Methyldecalin can be used for research on inflammatory conditions.
    2-Methyldecalin
  • HY-129949
    Aztreonam (lysine)
    		Inhibitor
    Aztreonam (lysine) is a monocyclic beta-lactam antibiotic, and has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam (lysine) is active against Gram-negative aerobic bacteria.
    Aztreonam (lysine)
  • HY-P5571
    Aurein 2.4
    		Inhibitor
    Aurein 2.4 is an antibiotic antimicrobial peptide. Aurein 2.4 is active against Gram-positive bacterial.
    Aurein 2.4
  • HY-B0875A
    Cefmenoxime
    		Inhibitor
    Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria.
    Cefmenoxime
  • HY-149801A
    Antibacterial agent 140 chloride
    		Inhibitor
    Antibacterial agent 140 chloride is a promising antibacterial agent. Antibacterial agent 140 chloride is also the first Ru-based AIEgen?photosensitizer?for simultaneous dual applications of?Gram-positive bacteria (G+)?detection. Antibacterial agent 140 chloride uniquely selective discriminates and efficient exterminates Gram-positive bacteria (G+)?from other bacteria due to its interaction with?lipoteichoic acids?(LTA). Antibacterial agent 140 chloride ?also possessed robust?antibacterial activity?for?G+ under?light irradiation.
    Antibacterial agent 140 chloride
  • HY-162328
    Antibacterial agent 194
    		Inhibitor
    Antibacterial agent 194 (Compound 19) is an antibacterial agent. Antibacterial agent 194 has potent anti-Mycobacterium tuberculosis (anti-Mtb) activity (MIC = 1 μg/mL).
    Antibacterial agent 194
  • HY-170586
    JAK05
    		Inhibitor
    JAK05 exhibits inhibitory activity against Helicobacter pylori, inhibits strains J63, J196 and J107 with MIC of 3-5 µg/mL. JAK05 exhibits binding affinity to H+/K+-ATPase, COX-1/2, TNF-α and PGE2, reveals antioxidant and anti-inflammatory activities. JAK05 exhibits anti-ulcer activity in rat ethanol-induced gastric ulcer models.
    JAK05
  • HY-144823
    Anti-MRSA agent 3
    		Inhibitor
    Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA.
    Anti-MRSA agent 3
  • HY-103643R
    Fumagillol (Standard)
    		Inhibitor
    Glucotropaeolin (potassium) (Standard) is the analytical standard of Glucotropaeolin (potassium). This product is intended for research and analytical applications. Glucotropaeolin potassium (Benzylglucosinolate potassium) , a glucosinolate contained in cruciferous vegetables, causes a moderate decrease in spontaneous DNA damage in animals.
    Fumagillol (Standard)
  • HY-144822
    Anti-MRSA agent 2
    		Inhibitor
    Anti-MRSA agent 2 (compound 14) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and relatively low cytotoxicity in normal cells. Anti-MRSA agent 2 has strong ability to destroy bacterial membrane and bind to genomic DNA.
    Anti-MRSA agent 2
  • HY-B1814
    Vitamin K5
    		Inhibitor
    Vitamin K5 (Synkamin) is a photosensitizer and a antimicrobial agent. Vitamin K5 is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 induces apoptosis of colon 26 cells. Vitamin K5 can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages.
    Vitamin K5
  • HY-N7224
    N-Formylfortimicin A
    		Inhibitor
    N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases.
    N-Formylfortimicin A
  • HY-173163
    (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium trifluoromethanesulfonate
    		Inhibitor
    (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) (Compound 4a) is a Gram-negative outer membrane permeabilizer with synergistic antibacterial activity through the blockage on LptA/LptC interaction via targeting Met47 in LptA. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) potentiates pol B against both wild-typed and MDR A. baumannii and E. coli strains. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) can be used as antibiotic adjuvants against MDR Gram-negative bacteria.
    (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium trifluoromethanesulfonate
  • HY-N0059S6
    D-Arabinose-d6
    		Inhibitor
    D-Arabinose-d6 is the deuterium labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose-d<sub>6</sub>
  • HY-105981
    Cefempidone
    		Inhibitor
    Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. Cefempidone exerts antibacterial activity by inhibiting penicillin-binding proteins in bacterial cell wall synthesis.
    Cefempidone
  • HY-161890
    Antimycobacterial agent-8
    		Inhibitor
    Antimycobacterial agent-8 (Compound 49) is an inhibitor for DNA gyrase. Antimycobacterial agent-8 exhibits antibacterial activity against Mycobacterium tuberculosis and M. abscessus with MIC90 of 2.5 μM and 0.63 μM. Antimycobacterial agent-8 exhibits good plasma protein binding ability in mice.
    Antimycobacterial agent-8
  • HY-B1128B
    Cefamandole lithium
    		Inhibitor
    Cefamandole (Cephamandole) lithium is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole lithium is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole lithium kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas, Proteus vulgaris and Providencia stuartii, and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole lithium in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole lithium is widely used in studies related to bacterial infections.
    Cefamandole lithium
  • HY-172768
    SCUT1-2
    		Inhibitor
    SCUT1-2 is a bifunctional antibacterial agent with good oral bioavailability in mice (F=56.8%). SCUT1-2 can kill the vegetative cells of C. difficile with a MIC of 0.06-0.50 μg/mL, and inhibit spore germination in vitro. SCUT1-2 could alleviate the symptoms of weight loss and diarrhea in mice caused by C. difficile infection (CDI) and prevent recurrent CDI.
    SCUT1-2
Cat. No. Product Name / Synonyms Application Reactivity