1. Anti-infection
  2. Bacterial
  3. Anti-MRSA agent 3

Anti-MRSA agent 3 

Cat. No.: HY-144823
Handling Instructions

Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA.

For research use only. We do not sell to patients.

Anti-MRSA agent 3 Chemical Structure

Anti-MRSA agent 3 Chemical Structure

CAS No. : 2416909-42-5

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Description

Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].

IC50 & Target

MIC: 0.098 μg/ml (MRSA)[1]

In Vivo

Anti-MRSA agent 3 has potent efficacy at a dose of 10 mg/kg (20% survival) in a mouse peritonitis model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

520.38

Formula

C29H18BrN3O2

CAS No.
SMILES

O=C1C2=C3NC4=C(C=C(C(NC5=C6C=CC=CC6=CC=C5)=O)C=C4)C3=CC=[N+]2C7=C1C=CC=C7.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Anti-MRSA agent 3
Cat. No.:
HY-144823
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