2416909-42-5
Chemical Structure
Anti-MRSA agent 3
- CAS No.: 2416909-42-5
- Formula:C29H18BrN3O2
- Molecular Weight:520.38
IUPAC Name: 9-(naphthalen-1-ylcarbamoyl)-13-oxo-12,13-dihydropyrido[1,2-a:3,4-b']diindol-5-ium bromide
InChIKey: HTLWDYLRLIWLQX-UHFFFAOYSA-N
SMILES: O=C1C2=C3NC4=C(C=C(C(NC5=C6C=CC=CC6=CC=C5)=O)C=C4)C3=CC=[N+]2C7=C1C=CC=C7.[Br-]
Biological Activity: Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].
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Anti-MRSA agent 3 | Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA. | |||||||||||||||||||||
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