1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14046
    Celesticetin B
    Inhibitor
    Celesticetin B is an antibiotic. Celesticetin B is mainly antibacterial against Gram-positive microorganisms.
    Celesticetin B
  • HY-N14538
    Saframycin E
    Inhibitor
    Saframycin E has the effect of anti-Gram-positive bacteria. Saframycin B also has weak activity against mycobacteria.
    Saframycin E
  • HY-N1190
    DL-Syringaresinol
    Inhibitor
    DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv.
    DL-Syringaresinol
  • HY-N14310
    Hongoquercin A
    Inhibitor
    Hongoquercin A is a sesquiterpene antibiotic. Hongoquercin A has moderate anti-Gram-positive bacteria activity with a MIC of 4-8 μg/mL.
    Hongoquercin A
  • HY-158980
    Antifungal agent 103
    Inhibitor
    Antifungal agent 103 (compound 7y) is a potent antifungal agent. Antifungal agent 103 inhibits R. solani with an EC50 of 0.47 μg/mL.
    Antifungal agent 103
  • HY-N14699
    Diphenicillin
    Inhibitor
    Diphenicillin (Ancillin (free acid); 2-Biphenylyl penicillin (free acid); SKF-12141 (free acid)) is a Penicillinase (HY-E70012)- resistant penicillin with antibacterial activity. Diphenicillin shows good antibacterial effects against Gram-positive cocci. Diphenicillin is promising for research of infectious diseases caused by Gram-positive cocci such as staphylococci, pneumococci, and group A streptococci.
    Diphenicillin
  • HY-P5546
    Lynronne-2
    Inhibitor
    Lynronne-2 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 32-256 μg/mL for methicillin-resistant MRSA strains). Lynronne-2 is also effective against P. aeruginosa infection
    Lynronne-2
  • HY-N12180
    Hodgkinsine B
    Inhibitor
    Hodgkinsine B is an opioid receptor agonist and NMDA receptor antagonist, which has analgesic and anti-injurial effects. In addition, Hodgkinsine B has antiviral, antibacterial and antifungal activities.
    Hodgkinsine B
  • HY-B0506R
    Nadifloxacin (Standard)
    Inhibitor
    Nadifloxacin (Standard) is the analytical standard of Nadifloxacin (HY-B0506). This product is intended for research and analytical applications. Nadifloxacin (OPC7251) is a broad-spectrum quinolone antibiotic. Nadifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, interfering with DNA replication. It also suppresses the production of proinflammatory cytokines (such as IL-1α, IL-6, and IL-8). Nadifloxacin exhibits antibacterial activity against various pathogens, including Propionibacterium acnes and Staphylococcus aureus. Nadifloxacin also exhibits anti-inflammatory activity. Nadifloxacin can be used in the research of skin infections such as acne vulgaris, folliculitis, and impetigo.
    Nadifloxacin (Standard)
  • HY-N14163
    Diperamycin
    Inhibitor
    Diperamycin has activity against Gram-positive bacteria, including Enterococcus seriolicida and MRSA (MICs of 0.10-0.20 μg/mL). Diperamycin also strongly inhibits the activity of L1210, P388, LS-180, KB, HeLaS3, Meth A and B16-BL6 (IC50s of 0.009-0.098 μg/mL).
    Diperamycin
  • HY-B0506S1
    Nadifloxacin-d5
    Inhibitor
    Nadifloxacin-d5 (OPC7251-d5) is deuterium labeled Nadifloxacin (HY-B0506). Nadifloxacin (OPC7251) is a broad-spectrum quinolone antibiotic. Nadifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, interfering with DNA replication. It also suppresses the production of proinflammatory cytokines (such as IL-1α, IL-6, and IL-8). Nadifloxacin exhibits antibacterial activity against various pathogens, including Propionibacterium acnes and Staphylococcus aureus. Nadifloxacin also exhibits anti-inflammatory activity. Nadifloxacin can be used in the research of skin infections such as acne vulgaris, folliculitis, and impetigo.
    Nadifloxacin-d<sub>5</sub>
  • HY-181100
    DHFR-IN-26
    Inhibitor
    DHFR-IN-26 is an Escherichia coli dihydrofolate reductase (ecDHFR) inhibitor with an IC50 of 0.75 nM. DHFR-IN-26 exerts broad-spectrum antibacterial activity. DHFR-IN-26 disrupts folate metabolism, nucleotide synthesis, and bacterial amino acid metabolic pathways. DHFR-IN-26 disrupts bacterial inner membranes, inhibited biofilm formation, and attenuated phage-related processes. DHFR-IN-26 shows lower toxicity to non-cancerous cells. DHFR-IN-26 can be used for the research of bacterial infections (including infections caused by methicillin-resistant Staphylococcus aureus, multidrug-resistant Escherichia coli, multidrug-resistant Pseudomonas aeruginosa, and lysogenic bacteria).
    DHFR-IN-26
  • HY-W587782
    Nonoxynol-9
    Inhibitor
    Nonoxynol-9 is a nonionic detergent. Nonoxynol-9 inhibits SOD activity. Nonoxynol-9 exhibits activity against diverse microbes and pathogens. Nonoxynol-9 can be used for the research of HIV infection.
    Nonoxynol-9
  • HY-N14905
    α-Prumycin hydrochloride
    Inhibitor
    α-Prumycin hydrochloride is a carbohydrate antibiotic. α-Prumycin hydrochloride has anti-fungal activity and weak anti-individual bacterial activity.
    α-Prumycin hydrochloride
  • HY-119387
    Chevalone B
    Inhibitor
    Chevalone B was isolated from the ethyl acetate extract of the marine sponge-associated fungus Aspergillus similanensis. The structure of Chevalone B was confirmed by 1D and 2D NMR spectroscopy. Chevalone B showed antimicrobial activity against Gram-positive and Gram-negative bacteria, Candida albicans, and multidrug-resistant strains from the environment. Studies on Chevalone B have shown its potential value in antimicrobial applications.
    Chevalone B
  • HY-120555
    Texaline
    Inhibitor
    Texaline is a active product that can be isolated from Amyris species of plants in the Caribbean. Texaline has antitubercular activity.
    Texaline
  • HY-W013549R
    6-Aminopenicillanic acid (Standard)
    Inhibitor
    6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.
    6-Aminopenicillanic acid (Standard)
  • HY-B0576R
    Sulfacetamide sodium (Standard)
    Inhibitor
    Sulfacetamide (Standard) (Sulphacetamide (Standard)) sodium is the analytical standard of Sulfacetamide sodium (HY-B0576). This product is intended for research and analytical applications. Sulfacetamide sodium is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium has antifungal and antibacterial activities.
    Sulfacetamide sodium (Standard)
  • HY-N14910
    Actiketal
    Inhibitor
    Actiketal is a glutarimide antibiotic that inhibits the incorporation of [3H]thymidine into EGF-stimulated Balb/MK cells.
    Actiketal
  • HY-N5186
    Cypemycin
    Inhibitor
    Cypemycin is a linaridin antibiotic that can inhibit cancer cell activity, inhibits P388 leukemia cells with IC50 of 1.3 μg/mL. Cypemycin can inhibit human tumor cells such as HeLa S3, HHCC-1, HCCS-M and Slex with IC50 of >25 μg/mL.
    Cypemycin
Cat. No. Product Name / Synonyms Application Reactivity