Cypemycin
Cypemycin is a linaridin antibiotic that can inhibit cancer cell activity, inhibits P388 leukemia cells with IC50 of 1.3 μg/mL. Cypemycin can inhibit human tumor cells such as HeLa S3, HHCC-1, HCCS-M and Slex with IC50 of >25 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 154277-21-1
- Formula: C99H154N24O24S
- Molecular Weight:2096.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 154277-21-1
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Molecular Weight 2096.49
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Formula C99H154N24O24S
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SMILES
O=C(N[C@H](C(N[C@H](C(N/C=C\SC1)=O)C(C)C)=O)CC(C)C)[C@H]1NC([C@H]([C@H](C)CC)NC(/C(NC([C@H](CO)NC(CNC([C@H](CCC(N)=O)NC([C@H]([C@H](C)CC)NC([C@H](C(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](C(C)C)NC(/C(NC([C@H]3N(CCC3)C(/C(NC([C@H](C)NC([C@H]4N(CCC4)C(/C(NC([C@H](C)N(C)C)=O)=C\C)=O)=O)=O)=C\C)=O)=O)=C\C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=C\C)=O)=O
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Structure Classification
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Initial Source
Streptomyces sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)