1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N13956
    Arylomycin A3
    Inhibitor
    Arylomycin A3 is a lipohexapeptide antibiotic against Gram-positive bacteria.
    Arylomycin A3
  • HY-105180A
    Lenapenem hydrochloride hydrate
    Inhibitor
    Lenapenem (BO-2727) hydrochloride hydrate, a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa.
    Lenapenem hydrochloride hydrate
  • HY-N5202
    Aspochalasin A
    Inhibitor
    Aspochalasin A has anti-bacterial and anti-fungal effects.
    Aspochalasin A
  • HY-109000B
    Afabicin diolamine
    Inhibitor
    Afabicin diolamine (Debio 1450 diolamine) is the proagent of Debio1452 (HY-16911), specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
    Afabicin diolamine
  • HY-122016A
    BRD-4592
    Inhibitor
    BRD-4592 is an allosteric inhibitor targeting Mycobacterium tuberculosis tryptophan synthase (TrpAB). BRD-4592 binds at the α-β-subunit interface of TrpAB, with an IC50 of 70.9 nM for the α-subunit and 22.6 nM for the β-subunit.
    BRD-4592
  • HY-14855S
    Tedizolid-13C,d3
    Inhibitor
    Tedizolid-13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
    Tedizolid-<sup>13</sup>C,d<sub>3</sub>
  • HY-B0522BR
    Ampicillin trihydrate (Standard)
    Inhibitor
    Ampicillin (trihydrate) (Standard) is the analytical standard of Ampicillin (trihydrate). This product is intended for research and analytical applications. Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
    Ampicillin trihydrate (Standard)
  • HY-B0356S2
    Ciprofloxacin-d4
    Inhibitor
    Ciprofloxacin-d4 (Bay-09867-d4) is deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin-d<sub>4</sub>
  • HY-W002071
    2-Quinoxalinecarboxylic acid
    Inhibitor 99.20%
    2-Quinoxalinecarboxylic acid is an antibacterial agent targeting Mycobacterium tuberculosis (MIC: >128 µg/mL). 2-Quinoxalinecarboxylic acid is promising for research of tuberculosis.
    2-Quinoxalinecarboxylic acid
  • HY-Y0532R
    N-Chlorosuccinimide (Standard)
    Inhibitor
    N-Chlorosuccinimide is a five-membered N-containing heterocyclic molecule. N-Chlorosuccinimide is a versatile reagent and can be used for different types of reactions, such as aliphatic and aromatic chlorination. N-Chlorosuccinimide can enhance the antimicrobial effect of Benzalkonium chloride (HY-B2232) on biofilm Pseudomonas aeruginosa.
    N-Chlorosuccinimide (Standard)
  • HY-10581CR
    Gatifloxacin sesquihydrate (Standard)
    Inhibitor
    Gatifloxacin (sesquihydrate) (Standard) is the analytical standard of Gatifloxacin (sesquihydrate). This product is intended for research and analytical applications. Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis?in vivo.
    Gatifloxacin sesquihydrate (Standard)
  • HY-102072
    GKL003
    Inhibitor
    GKL003 is a bacterial transcription inhibitor that targets the RNAP-σ interaction interface, with a Ki of 5.79 nM. GKL003 specifically binds to the RNAP β' clamp helix region at the σA factor binding site, blocks the formation of RNAP holoenzyme, and inhibits the formation of bacterial transcription initiation complexes. GKL003 inhibits the growth of both Gram-positive and Gram-negative bacterial cells, and also exhibits activity against drug-resistant strains.
    GKL003
  • HY-170993
    Antimicrobial agent-39
    Inhibitor
    Antimicrobial agent-39 (Compound 8i) is an antibiotic that targets 50S ribosomal subunit and inhibits bacterial protein synthesis. Antimicrobial agent-39 disrupts bacterial cell membranes, leads to leakage of cell contents, thereby exhibiting board-spectrum actibacterial activity. Antimicrobial agent-39 targets organic cation transporters (OCTs), accumulates in infected kidneys, thereby ameliorating pyelonephritis in mouse models.
    Antimicrobial agent-39
  • HY-101985R
    BV02 (Standard)
    Inhibitor
    BV02 (Standard) is the analytical standard of BV02 (HY-101985). This product is intended for research and analytical applications. BV02 is a 14-3-3 inhibitor and an antibacterial agent. BV02 enhances the cleavage of PARP and caspase-3. BV02 induces Apoptosis, Autophagy, and enhances Akt activation. BV02 has anti-B. melitensis infection and epilepsy-promoting effects. BV02 can also be used in colitis research.
    BV02 (Standard)
  • HY-119968
    Granaticin
    Inhibitor
    Granaticin A inhibits the initial stage of RNA biosynthesis, has anti-Gram-positive bacteria, Mycobacterium (weak) and Vaginal trichomonas activity, but also can inhibit tumor cells.
    Granaticin
  • HY-122428
    Samandarone
    Inhibitor
    Samandarone is an alkaloid that can be isolated from the skin gland secretions of Salammedra maculosa and Leptodactylus pentadactylus, which exhibits antimicrobial activity.
    Samandarone
  • HY-N14732
    Demycarosyl platenomycin
    Inhibitor
    Demycarosylplatenomycin (DM-PLM) is an antibiotic with weak activity against Gram-positive bacteria.
    Demycarosyl platenomycin
  • HY-N14468
    Pneumocandin B2
    Inhibitor
    Pneumocandin B2 is a lipopeptide antibiotic. Pneumocandin B2 has a strong anti-Candida effect. Pneumocandin B2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL.
    Pneumocandin B2
  • HY-17592R
    Bithionol (Standard)
    Inhibitor
    Bithionol (Standard) is the analytical standard of Bithionol. This product is intended for research and analytical applications. Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM).
    Bithionol (Standard)
  • HY-13588R
    Cefsulodin sodium (Standard)
    Inhibitor
    Cefsulodin (sodium) (Standard) is the analytical standard of Cefsulodin (sodium). This product is intended for research and analytical applications. Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM.
    Cefsulodin sodium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity