Afabicin diolamine
Afabicin diolamine (Debio 1450 diolamine) is the proagent of Debio1452 (HY-16911), specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
For research use only. We do not sell to patients.
- CAS No.: 1518800-36-6
- Formula: C27H38N5O9P
- Molecular Weight:607.59
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 1518800-36-6
-
Molecular Weight 607.59
-
Formula C27H38N5O9P
-
SMILES
OCCN.O=P(O)(O)OCN1C2=NC=C(/C=C/C(N(C)CC3=C(C)C4=CC=CC=C4O3)=O)C=C2CCC1=O.OCCN
-
Synonyms
Debio 1450 diolamine; AFN-1720 diolamine
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)