2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. 상품명 효과 Purity Chemical Structure
  • HY-162508
    KSK-104
    		Inhibitor
    KSK-104 has potent antibacterial activity against Mycobacterium tuberculosis (MIC=0.78 μM). The role of KSK-104 is mainly involved in the synthesis and recovery pathways of pyridoxal 5'-phosphate (PLP), PLP-dependent enzymes and oxidative stress networks. KSK-104, as a candidate molecule for novel anti-tuberculosis drugs, can be used to develop research against drug-resistant mycobacterium tuberculosis.
    KSK-104
  • HY-143232
    Antibacterial agent 73
    		Inhibitor
    Antibacterial agent 73 (compound 7a) is a potent antimicrobial agent. Antibacterial agent 73 exhibits very good antitubercular activity (MIC=0.65 µg/mL) against Mtb H37Rv. Antibacterial agent 73 shows good activity against fungal and bacterial. Antibacterial agent 73 also shows cytotoxicity in MCF-7 breast cancer cell lines, with IC50 of 8.20 μM.
    Antibacterial agent 73
  • HY-P11600
    SGNLTKYWKKIWKPGIKKWIK
    		Inhibitor
    SGNLTKYWKKIWKPGIKKWIK is a thymidylate kinase (TMK)-targeting antimicrobial peptide with a KD value of 4.721 μM. SGNLTKYWKKIWKPGIKKWIK exerts antimicrobial effects through multiple mechanisms, including membrane disruption, induction of ROS, and DNA binding. SGNLTKYWKKIWKPGIKKWIK shows remarkable activity against Gram-negative bacteria, possesses good biocompatibility, and rarely induces drug resistance. SGNLTKYWKKIWKPGIKKWIK can be used for research on Gram-negative bacterial infections.
    SGNLTKYWKKIWKPGIKKWIK
  • HY-112225
    Narasin sodium
    Narasin sodium is a cationic ionophore and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin sodium has antimicrobial and anticancer activity.
    Narasin sodium
  • HY-163197
    JSF-2827
    		Inhibitor
    JSF-2827 is a benzothiophene with antibacterial activity against Enterococcus faecium.
    JSF-2827
  • HY-151614
    Anti-infective agent 7
    		Inhibitor
    Anti-infective agent 7 is a potent anti-infectious agent. Anti-infective agent 7 has anti-infection activity against P. falciparum (IC50=2.5 μM) and M. tuberculosis (MIC=9 μM).
    Anti-infective agent 7
  • HY-W436428
    V-161
    		Inhibitor
    V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 µg/mL and 4 µg/mL. V-161 inhibits colonization of VRE in mouse small intestine.
    V-161
  • HY-149811
    AcrB-IN-3
    		Inhibitor
    Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model.
    AcrB-IN-3
  • HY-P5576
    Aurein 3.3
    		Inhibitor
    Aurein 3.3 is an antibiotic antimicrobial peptide. Aurein 3.3 also has anticancer activity.
    Aurein 3.3
  • HY-152495
    MenA-IN-1
    		Inhibitor
    MenA IN-1 is an effective inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB) with an IC50 value of 13 µM and an GIC50 value of 8 µM. MenA IN-1 can be used to curb the continuous spread of tuberculosis.
    MenA-IN-1
  • HY-100821
    2,4-Dihydroxyphenylacetylasparagine
    		Inhibitor
    2,4-Dihydroxyphenylacetylasparagine is a potent and selective antagonist of glutamate. 2,4-Dihydroxyphenylacetylasparagine inhibits glutamate binding to rat brain synaptic membranes.
    2,4-Dihydroxyphenylacetylasparagine
  • HY-N2805
    9-Oxonerolidol
    		Inhibitor
    9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic.
    9-Oxonerolidol
  • HY-D3391
    RMR-Tre
    		Substrate
    RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research.
    RMR-Tre
  • HY-121071
    Ascamycin
    		Inhibitor
    Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively.
    Ascamycin
  • HY-B1436S
    Nifuroxazide-d4
    		Inhibitor
    Nifuroxazide-d4 is the deuterium labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
    Nifuroxazide-d<sub>4</sub>
  • HY-N17584
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside
    		Inhibitor
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside (compound 1) is a lignan found in the dried roots of Pulsatilla koreana and Sortase A inhibitor with an IC50 of 67.7 μM against Streptococcus mutans OMZ65 Sortase A. (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside can be used for the research of dental caries.
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside
  • HY-147000
    DNA Gyrase-IN-1
    		Inhibitor
    DNA Gyrase-IN-1 (compound 42) is a potent and selective DNA gyrase inhibitor with an IC50 value of 2.6 µM. DNA Gyrase-IN-1 has high inhibitory activity against Mycobacterium tuberculosis (Mtb) with MIC of 0.49 µM. DNA Gyrase-IN-1 can be used for researching tuberculosis.
    DNA Gyrase-IN-1
  • HY-157808
    Antibacterial agent 185
    		Inhibitor
    Antibacterial agent 185 (compound IP-01) is a potent antibacterial agent. Antibacterial agent 185 inhibits filamentous temperature-sensitive mutant Z (FtsZ) polymerization and bundling by increasing GTP hydrolysis. Antibacterial agent 185 inhibits Streptococcus pneumoniae and shows narrow-spectrum activity.
    Antibacterial agent 185
  • HY-147777
    14α-Demethylase/DNA Gyrase-IN-2
    		Inhibitor
    14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-2 has antimicrobial activities.
    14α-Demethylase/DNA Gyrase-IN-2
  • HY-146301
    Mt KARI-IN-5
    		Inhibitor
    Mt KARI-IN-5 (compound 6c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 4.72 μM. Mt KARI-IN-5 has inhibitory activity against Mtb H37Rv (MIC = 1.56 μM) and low cytotoxicity (HEK IC50 > 64 μg/mL)
    Mt KARI-IN-5
Cat. No. 상품명 / Synonyms Application Reactivity