DNA Gyrase-IN-1
DNA Gyrase-IN-1 (compound 42) is a potent and selective DNA gyrase inhibitor with an IC50 value of 2.6 µM. DNA Gyrase-IN-1 has high inhibitory activity against Mycobacterium tuberculosis (Mtb) with MIC of 0.49 µM. DNA Gyrase-IN-1 can be used for researching tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 3031486-11-7
- Formula: C24H24FN7O6
- Molecular Weight:525.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>300 μM
Compound: 42
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 35500229] |
Chemical Information
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CAS No. 3031486-11-7
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Molecular Weight 525.49
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Formula C24H24FN7O6
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SMILES
C[C@@H]1N([C@@H](CN2C3=C(C4=C(C=C3CC5([C@]21[H])C(NC(NC5=O)=O)=O)C(OC[C@H]6NC(CC6)=O)=NO4)F)C)C#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)