AcrB-IN-3
Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2890177-94-1
- 화학식: C30H33NO7
- 분자량:519.59
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
All Parasite Isoforms
More
Biological Activity
Efflux pump-IN-3 (compound G10) (8-128 μg/mL) shows outstanding antibacterial synergism with at least one of the antibiotics (ERY, LEV and MIN). Efflux pump-IN-3 show antibacterial synergism with MIN, and reduces the MIC value of ERY by 4-fold at 64 μg/mL[1].
Efflux pump-IN-3 (50 μM, 100 μM) shows strong inhibitory activity at the lowest concentration of 50 μM, to inhibit Nile Red efflux[1].
Efflux pump-IN-3 (4-256 μg/mL) does not cause hemolysis of mice red blood cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2890177-94-1
-
분자량 519.59
-
화학식 C30H33NO7
-
SMILES
O=C(C1=CC(OCCCOC2=CC=CC3=C2C=C(C(N4CCOCC4)=O)C5=C3OC(C)(CC5)C)=CC=C1)O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AcrB-IN-3 Related Classifications
HY-149811 Related Classifications
Powered by Bioz