Antibacterial agent 185
Antibacterial agent 185 (compound IP-01) is a potent antibacterial agent. Antibacterial agent 185 inhibits filamentous temperature-sensitive mutant Z (FtsZ) polymerization and bundling by increasing GTP hydrolysis. Antibacterial agent 185 inhibits Streptococcus pneumoniae and shows narrow-spectrum activity.
For research use only. We do not sell to patients.
- Formula: C18H17BrN2O3S
- Molecular Weight:421.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
41 μM
Compound: IP-01
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs by SRB assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs by SRB assay
|
[PMID: 38350359] |
Chemical Information
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Molecular Weight 421.31
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Formula C18H17BrN2O3S
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SMILES
CCOC(C1=C(N=C2C=CC(Br)=CN21)CSC3=CC=C(C=C3)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)