2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1257R
    Cefmetazole sodium (Standard)
    		Inhibitor
    Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections.
    Cefmetazole sodium (Standard)
  • HY-172826
    Anti-MRSA agent 26
    		Antagonist
    Anti-MRSA agent 26 is a potent anti-MRSA agent with MIC <0.015 μg/mL. Anti-MRSA agent 26 has superior activity against a broad range of Gram-positive pathogens and shows no cytotoxicity in three mammalian cell lines (Caco-2, DU-145 and MDCKII MDR1 cells) at 10 μM. Anti-MRSA agent 26 has a robust TAP pharmacophore and an excellent antibacterial activity in Staphylococcus aureus skin infection mice model.
    Anti-MRSA agent 26
  • HY-B0356G
    Ciprofloxacin (GMP)
    		Inhibitor
    Ciprofloxacin GMP is Ciprofloxacin (HY-B0356) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Ciprofloxacin (Bay-09867) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity.
    Ciprofloxacin (GMP)
  • HY-155346
    Free radical scavenger 1
    		Inhibitor
    Free radical scavenger 1 (compound 8) shows scavenging activity against the DPPH radical, with the IC50 of 43.39 μg/ml.
    Free radical scavenger 1
  • HY-W247616
    (4-Aminobenzyl)phosphonic acid
    		Inhibitor 98.0%
    (4-Aminobenzyl)phosphonic acid is a bioactive compound with potential anticancer and antibacterial activities. (4-Aminobenzyl)phosphonic acid is widely used in compound synthesis to develop new inhibition methods. Through its unique structure, (4-Aminobenzyl)phosphonic acid can effectively interact with biological targets.
    (4-Aminobenzyl)phosphonic acid
  • HY-147819
    DNA Gyrase-IN-3
    		Inhibitor
    DNA Gyrase-IN-3 (Compound 28) is a bacterial DNA gyrase B inhibitor with IC50s of 5.41-15.64 µM for E. coli DNA gyrase. Anti-tubercular and antibacterial activity.
    DNA Gyrase-IN-3
  • HY-N19064
    Chlorophytum borivilianum extract
    Chlorophytum borivilianum extract is rich in saponins, alkaloids and glycosides, and has aphrodisiac properties.
    Chlorophytum borivilianum extract
  • HY-149271
    Anti-MRSA agent 7
    		Inhibitor
    Anti-MRSA agent 7 (Compound 12) is a potent antibacterial agent. Anti-MRSA agent 7 inhibits S. aureus DNA gyrase, E. coli DNA gyrase, S. aureus topo IV and E. coli topo IV with IC50s of 0.185, 0.365, 0.341 and 0.059 μM, respectively.
    Anti-MRSA agent 7
  • HY-N6725S
    Sterigmatocystine-13C18
    		Inhibitor
    Sterigmatocystine-13C18 is 13C labeled 2,6-Dimethoxyphenol (HY-W003972). 2,6-Dimethoxyphenol is a phenolic compound that is extensively used for the measurement of laccase activity.
    Sterigmatocystine-<sup>13</sup>C<sub>18</sub>
  • HY-W013780S
    Fmoc-Pro-OH-1-13C
    		Inhibitor
    Fmoc-Pro-OH-13C is a 13C-labeled Fmoc-Pro-OH (HY-W013780). Fmoc-Pro-OH is a proline derivative.
    Fmoc-Pro-OH-1-<sup>13</sup>C
  • HY-123022
    Tomopenem
    		Inhibitor
    Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL). Antianaerobic activity.
    Tomopenem
  • HY-D2987
    BacGO
    BacGO is a highly selective, wash free fluorescent probe for Gram positive bacteria. BacGO binds to the carbohydrate structure in peptidoglycan through boric acid and exhibits depolymerization induced luminescence (DIE) properties. BacGO can be used for imaging complex environmental samples (such as activated sludge) and flat plate bacteria without affecting bacterial activity.
    BacGO
  • HY-127160R
    Benzoxonium chloride (Standard)
    		Inhibitor
    Benzoxonium (chloride) (Standard) is the analytical standard of Benzoxonium (chloride). This product is intended for research and analytical applications. Benzoxonium chloride is an anti-leishmanial agent. Benzoxonium chloride inhibits bacteria, certain protozoa, yeasts and non-spore forming organisms.
    Benzoxonium chloride (Standard)
  • HY-168853
    Antibacterial agent 261
    		Inhibitor
    Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.5 and 10.6 nM for S. aureus and E. coli, respectively.
    Antibacterial agent 261
  • HY-111154
    BPH-608
    		Inhibitor
    BPH-608 is a bacterial undecenyl diphosphate synthase (UPPS) inhibitor (IC50=590 nM) with antibacterial activity.
    BPH-608
  • HY-17395B
    Terbinafine lactate
    		Inhibitor
    Terbinafine lactate (TDT 067 lactate) is an orally active and potent antifungal agent. Terbinafine lactate is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine lactate also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine (lactate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine lactate
  • HY-151514
    Antituberculosis agent-5
    		Inhibitor 99.76%
    Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL.
    Antituberculosis agent-5
  • HY-W686760A
    Bromamphenicol
    		Inhibitor
    Bromamphenicol (Compound Ib) is a derivative of Chloramphenicol (HY-B0239), and exhibits antibacterial activity. Bromamphenicol binds to S50 ribosomal subunit, interfers with the activity of peptidyl transferase, and exhibits inhibitory activity against protein synthesis.
    Bromamphenicol
  • HY-P10907
    Zaloganan
    		Inhibitor
    Zaloganan exhibits board-spectrum antibacterial activity through disruption of bacterial membranes.
    Zaloganan
  • HY-B0455AR
    Lomefloxacin (Standard)
    		Inhibitor
    Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc..
    Lomefloxacin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity