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Cat. No.: HY-111154

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BPH-608

BPH-608 is a bacterial undecenyl diphosphate synthase (UPPS) inhibitor (IC₅₀=590 nM) with antibacterial activity.

For research use only. We do not sell to patients.

CAS No.: 911783-02-3
Formula: C₂₀H₂₀O₇P₂
Molecular Weight:434.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BPH-608 Chemical Structure

CAS No.: 911783-02-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

BPH-608 is a bacterial undecenyl diphosphate synthase (UPPS) inhibitor (IC₅₀=590 nM) with antibacterial activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	152 μM Compound: 58	Antiproliferative activity against human MCF7 cell line by MTT assay Antiproliferative activity against human MCF7 cell line by MTT assay	[PMID: 16970405]
NCI-H460	IC₅₀	140 μM Compound: 58	Antiproliferative activity against human NCI-H460 cell line by MTT assay Antiproliferative activity against human NCI-H460 cell line by MTT assay	[PMID: 16970405]
SF-268	IC₅₀	130 μM Compound: 58	Antiproliferative activity against human SF-268 cell line by MTT assay Antiproliferative activity against human SF-268 cell line by MTT assay	[PMID: 16970405]

Chemical Information

CAS No. 911783-02-3
Molecular Weight 434.32
Formula C₂₀H₂₀O₇P₂
SMILES

O=P(O)(C(CC1=CC(C2=CC=CC(C3=CC=CC=C3)=C2)=CC=C1)(P(O)(O)=O)O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. HY Chang, et al. Structure, catalysis, and inhibition mechanism of prenyltransferase. IUBMB life 73.1 (2021): 40-63. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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