1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-151458
    VEGFR-2/DHFR-IN-1
    Inhibitor
    VEGFR-2/DHFR-IN-1 (compound 8b) is an inhibitor of VEGFR-2 and DHFR with IC50s of 0.384 and 7.881 μM, respectively. VEGFR-2/DHFR-IN-1 shows good antibacterial activities against Escherichia coli, Streptococcus faecalis, Salmonella enterica, MSSA and MRSA with MIC values of 16, 16, 16, 8, and 16 μg/mL, respectively. VEGFR-2/DHFR-IN-1 exhibits good cytotoxic activities against C26, HepG2, and MCF7 cancer cell lines with IC50 values of 2.97-7.12 μM. VEGFR-2/DHFR-IN-1 can be used for the research of cancer.
    VEGFR-2/DHFR-IN-1
  • HY-131478
    Pyruvic acid semicarbazone
    Inhibitor
    Pyruvic acid semicarbazone is an inhibitor of bacterial and fungal. Pyruvic acid semicarbazone is promising for research of anti-infective agents, cancers, and plant growth regulation.
    Pyruvic acid semicarbazone
  • HY-144701R
    SABA1 (Standard)
    Inhibitor
    Fluopicolide (Standard) is the analytical standard of Fluopicolide. This product is intended for research and analytical applications. Fluopicolide is the active compound.
    SABA1 (Standard)
  • HY-151280
    Antifungal agent 37
    Inhibitor
    Antifungal agent 37 is a geterocyclic disulfide, with antifungal activity.
    Antifungal agent 37
  • HY-124814
    C215
    99.63%
    C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages.
    C215
  • HY-113795
    Aldgamycin E
    Inhibitor
    Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity.
    Aldgamycin E
  • HY-180539
    JT71
    Inhibitor 99.30%
    JT71 is an inhibitor of the transcriptional activator MrkH of type III fimbriae in Klebsiella pneumoniae. JT71 reduces the activity of the mrkA promoter in Klebsiella pneumoniae, effectively inhibiting the formation of biofilms by Klebsiella pneumoniae, while not affecting the cell's viability. JT71 can be used for research on Klebsiella pneumoniae infections.
    JT71
  • HY-W025784R
    Kalibor (Standard)
    Inhibitor
    (Sodium tetraphenylborate; Tetraphenylboron sodium) (Standard) is the analytical standard of Kalibor (HY-W025784). This product is intended for research and analytical applications. Kalibor is a boron-based salt and antibacterial agent. Kalibor exerts activity against Neisseria meningitidis and Neisseria gonorrhoeae. Kalibor facilitates boron uptake by Neisseria meningitidis cells. Kalibor reduces bacterial burden in a mouse model of Neisseria meningitidis bacteremia. Kalibor can be used for the research of bacterial infection, such as meningococcal bacteremia.
    Kalibor (Standard)
  • HY-P10814
    MciZ (B. subtilis)
    Inhibitor
    MciZ (B. subtilis), a 40-amino-acid peptide, inhibits the GTPase activity of FtsZ that prevents inappropriate Z-ring formation during sporulation.
    MciZ (B. subtilis)
  • HY-158320
    T3SS-IN-5
    T3SS-IN-5 (Compound F9) is a specific inhibitor of the type III secretion system (T3SS). T3SS-IN-5 reduces bacterial pathogenicity without affecting bacterial viability by inhibiting the expression of genes associated with T3SS.
    T3SS-IN-5
  • HY-117990
    GSK572A
    Inhibitor
    GSK572A is a potent EchA6 inhibitor with an Kd value of 1.9 µM. GSK572A shows anti-tubercular activity.
    GSK572A
  • HY-174219
    BT-33
    Inhibitor
    BT-33 is a fuorinated macrobicyclic oxepanoprolinamide antibiotic with broad-spectrum activity against multidrug-resistant bacterial pathogens.
    BT-33
  • HY-134947
    11-Hydroxynovobiocin
    Inhibitor
    11-Hydroxynovobiocin has anti-Gram-negative bacteria effect.
    11-Hydroxynovobiocin
  • HY-183305
    Antibiofilm-IN-1
    Inhibitor
    Antibiofilm-IN-1 (Compound 10) is a biofilm inhibitor and Antibacterial agent. Antibiofilm-IN-1 potently inhibits biofilm formation by Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa.
    Antibiofilm-IN-1
  • HY-146165
    Metallo-β-lactamase-IN-8
    Inhibitor
    Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity.
    Metallo-β-lactamase-IN-8
  • HY-151960
    Antitubercular agent-36
    Inhibitor
    Antitubercular agent-36 (compound 53) is an antitubercular agent. Antitubercular agent-36 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL. Antitubercular agent-36 can be used for the research of tuberculosis.
    Antitubercular agent-36
  • HY-144721
    Antitubercular agent-11
    Antitubercular agent-11 (Compound 1e) is an antitubercular agent. Antitubercular agent-11 with a bulkier electron-donating group (Bu-t) demonstrated the best MIC value of 0.060 μg/mL.
    Antitubercular agent-11
  • HY-17358S1
    Loteprednol Etabonate-d3
    Inhibitor
    Loteprednol Etabonate-d3 is the deuterium labeled Loteprednol Etabonate. Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology.
    Loteprednol Etabonate-d<sub>3</sub>
  • HY-13579R
    BTZ043 (Standard)
    Inhibitor
    BTZ043 (Standard) is the analytical standard of BTZ043. This product is intended for research and analytical applications. BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.
    BTZ043 (Standard)
  • HY-116933
    Murrayanol
    Inhibitor
    Murrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial.
    Murrayanol
Cat. No. Product Name / Synonyms Application Reactivity