C215
Based on 1 Customer Validation
C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages.
For research use only. We do not sell to patients.
- Purity: 99.63%
- CAS No.: 912780-51-9
- Formula: C17H17Cl2N3
- Molecular Weight:334.24
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 912780-51-9
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Appearance Solid
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Molecular Weight 334.24
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Formula C17H17Cl2N3
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Color White to off-white
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SMILES
CCCN1C2=CC=C(NCC3=CC=C(Cl)C=C3Cl)C=C2N=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 62.5 mg/mL (186.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9919 mL | 14.9593 mL | 29.9186 mL | 74.7966 mL |
| 5 mM | 0.5984 mL | 2.9919 mL | 5.9837 mL | 14.9593 mL | |
| 10 mM | 0.2992 mL | 1.4959 mL | 2.9919 mL | 7.4797 mL | |
| 15 mM | 0.1995 mL | 0.9973 mL | 1.9946 mL | 4.9864 mL | |
| 20 mM | 0.1496 mL | 0.7480 mL | 1.4959 mL | 3.7398 mL | |
| 25 mM | 0.1197 mL | 0.5984 mL | 1.1967 mL | 2.9919 mL | |
| 30 mM | 0.0997 mL | 0.4986 mL | 0.9973 mL | 2.4932 mL | |
| 40 mM | 0.0748 mL | 0.3740 mL | 0.7480 mL | 1.8699 mL | |
| 50 mM | 0.0598 mL | 0.2992 mL | 0.5984 mL | 1.4959 mL | |
| 60 mM | 0.0499 mL | 0.2493 mL | 0.4986 mL | 1.2466 mL | |
| 80 mM | 0.0374 mL | 0.1870 mL | 0.3740 mL | 0.9350 mL | |
| 100 mM | 0.0299 mL | 0.1496 mL | 0.2992 mL | 0.7480 mL |
C215 Related Classifications
HY-124814 Related Classifications
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