912780-51-9
Chemical Structure
C215
- CAS No.: 912780-51-9
- Formula:C17H17Cl2N3
- Molecular Weight:334.24
IUPAC Name: N-(2,4-dichlorobenzyl)-1-propyl-1H-benzo[d]imidazol-5-amine
InChIKey: PWEPSIFNTIQCNN-UHFFFAOYSA-N
SMILES: CCCN1C2=CC=C(NCC3=CC=C(Cl)C=C3Cl)C=C2N=C1
Biological Activity: C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages[1].
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C215 | 99.63% | C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages. | ||||||||||||||||||||
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Keywords