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Cat. No.: HY-158320

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T3SS-IN-5

T3SS-IN-5 (Compound F9) is a specific inhibitor of the type III secretion system (T3SS). T3SS-IN-5 reduces bacterial pathogenicity without affecting bacterial viability by inhibiting the expression of genes associated with T3SS.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₆H₁₄N₂OS₂
분자량:314.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

T3SS-IN-5 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

T3SS-IN-5 (200 μM; 48 h) has no statistically significant effect on the viability of Xcc^[1].
T3SS-IN-5 (200 μM; 5 d) causes a significant reduction in Xcc-jx-6-induced hypersensitive response (HR) in Nicotiana benthamiana^[1].
T3SS-IN-5 (200 μM; 4-7 d) reduces the ulcerative symptoms of orach orange and is more effective than bismerthiazol at the same concentration^[1].
T3SS-IN-5 (200 μM; 16 h) significantly reduces the relative incidence of Xcc^[1].
T3SS-IN-5 (200 μM; 48 h-5 d) does not affect other virulence factors of Xcc, including extracellular enzymes activity, EPS activity, motility, and biofilm formation^[1].
T3SS-IN-5 (100-200 μM; 4 d) combines with Burkholderia anthina hN-8 can further improve the inhibition of Xcc^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR^[1]

Cell Line:

hrp cluster
Concentration:

200 μM
Incubation Time:

16 h
Result:

Significantly reduced the expression levels of key T3SS genes (hrpG, hrpX, hrpE, hrcC, hrcT, and hpa1) in the Xcc.
Significantly reduced the expression of the critical disease susceptibility gene, Citrus sinensis lateral organ boundary 1 (CsLOB1).

Related Protocols :

Chemical Information

분자량 314.43
화학식 C₁₆H₁₄N₂OS₂
SMILES

OC(C1=NN=C(SCC2=CC=CC=C2)S1)C3=CC=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang YQ, et al. Design and Synthesis of Mandelic Acid Derivatives for Suppression of Virulence via T3SS against Citrus Canker. J Agric Food Chem. 2024 May 1;72(17):9611-9620. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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