2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17021A
    Esomeprazole magnesium salt
    Esomeprazole magnesium salt ((S)-Omeprazole magnesium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole magnesium salt has the potential for symptomatic gastroesophageal reflux disease research.
    Esomeprazole magnesium salt
  • HY-163625
    Mtb-IN-7
    		Inhibitor
    Mtb-IN-7 (compoun R7) is a MAO-A/MAO-B inhibitor with the IC50 values over 40 μM. Mtb-IN-7 shows antimycobacterial activity against M. tuberculosis H37Rv with the MIC of 2.01 μM.
    Mtb-IN-7
  • HY-N14481
    Phenelfamycin B
    		Inhibitor
    Phenelfamycins B is an antibiotic with anti-eutrophic bacterial activity.
    Phenelfamycin B
  • HY-B0113S2
    Omeprazole sulfone (methoxy-d3)
    		Inhibitor 99.70%
    Omeprazole sulfone (methoxy-d3) is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (H 16868) is an orally active H+,K+-ATPase inhibitor and a proton pump inhibitor. Omeprazole sulfone competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole sulfone inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole sulfone inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole sulfone alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole sulfone aslo has neuroprotective and antibacterial effects.
    Omeprazole sulfone (methoxy-d<sub>3</sub>)
  • HY-N15069
    4'-O-Demethyldianemycin
    		Inhibitor
    4'-O-Demethyldianemycin (TM-531B) is a polyether antibiotic found in Streptomyces hygroscopicus TM-531. Activity against Gram-positive bacteria.
    4'-O-Demethyldianemycin
  • HY-116168
    Aldecalmycin
    		Inhibitor
    Aldecalmycin is an antibiotic showing antimicrobial activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs values of 6.25-25 μg/mL.
    Aldecalmycin
  • HY-B1300R
    Cefonicid sodium (Standard)
    		Inhibitor
    Cefonicid sodium (Standard) is the analytical standard of Cefonicid sodium (HY-B1300). This product is intended for research and analytical applications. Cefonicid sodium is a long-acting cephalosporin antibiotic. Cefonicid sodium also acts as a noncompetitive class I β-lactamase inhibitor with a Ki value of 0.8 μM. Cefonicid sodium exhibits broad-spectrum antimicrobial activity and is effective against a variety of Gram-positive and Gram-negative bacteria. Cefonicid sodium can be used for research on infections.
    Cefonicid sodium (Standard)
  • HY-N0683S6
    α-Vitamin E-d11
    		Inhibitor
    α-Vitamin E-d11 ((+)-α-Tocopherol-d11) is the deuterium labeled α-Vitamin E (HY-N0683). α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant.
    α-Vitamin E-d<sub>11</sub>
  • HY-W782391
    Linolenyl alcohol
    		Inhibitor
    Linolenyl alcohol is an unsaturated alcohol that inhibits Gram-positive bacteria.
    Linolenyl alcohol
  • HY-180151
    Antibacterial agent 306
    		Inhibitor
    Antibacterial agent 306 (Compound 8c), a lactate dehydrogenase inhibitor, is a highly effective antibacterial agent, especially effective against Gram-positive bacteria. Antibacterial agent 306 exhibits MIC against Staphylococcus aureus of as low as 1 μg/mL. Antibacterial agent 306 can not only damage membrane integrity and block the replication of DNA by intercalation, but also make reactive oxygen species (ROS) burst. Antibacterial agent 306 can be used for research on anti-multi-drug resistant bacteria.
    Antibacterial agent 306
  • HY-155462
    hERG-IN-1
    		Inhibitor
    hERG-IN-1 (compound 2a) is an antibacterial agent and inhibitor of hERG. hERG-IN-1 inhibits pulmonary infection caused by Pseudomonas aeruginosa strain ATCC 27853.
    hERG-IN-1
  • HY-113619
    ABT-255 free base
    		Inhibitor
    ABT-255 free base is an orally active anti-bacterial agent. ABT-255 free base exhibits potent in vitro potency (MIC = 0.016-0.031 μg/mL) against drug-susceptible and Rifampin (HY-B0272)- or Ethambutol (HY-B0535)-resistant Mycobacterium tuberculosis. ABT-255 free base shows efficacy against S. aureus, S. pneumoniae and E. coli and reduces viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. ABT-255 free base can be used for the study of pulmonary tuberculosis.
    ABT-255 free base
  • HY-W722245
    Pyochelin
    Pyochelin is a salicylate-based nonribosomal peptide siderophore produced by Pseudomonas aeruginosa. Pyochelin chelates Fe3+ and transports it back into bacterial cells, providing the iron essential for bacterial survival. Pyochelin can also chelate other metals such as Zn2+, Co2+, and Ni2+, which helps bacteria maintain intracellular metal ion homeostasis by chelating and excreting excess metals in response to toxic metal stress. Pyochelin can be used in studies related to Pseudomonas aeruginosa infection.
    Pyochelin
  • HY-145301
    Mycobactin-IN-1
    		Inhibitor 98.96%
    Mycobactin-IN-1, a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway. Mycobactin-IN-1 inhibits whole-cell drug efflux pumps in M. smegmatis. Mycobactin-IN-1 eradicates intracellularly surviving mycobacteria. Mycobactin-IN-1 shows an excellent in vivo pharmacokinetic profile. Mycobactin-IN-1 can be used for the research of tuberculosis.
    Mycobactin-IN-1
  • HY-129814
    MM 42842 free acid
    		Inhibitor
    MM 42842 free acid is a member of the monobactam family of β-lactam antibiotics.
    MM 42842 free acid
  • HY-B0958R
    Mupirocin (Standard)
    		Inhibitor
    Mupirocin (Standard) is the analytical standard of Mupirocin (HY-B0958). This product is intended for research and analytical applications. Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis.
    Mupirocin (Standard)
  • HY-115407
    Cochliodone A
    		Inhibitor
    Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC50s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2).
    Cochliodone A
  • HY-17507S2
    Pantoprazole-d8
    Pantoprazole-d8 (BY1023-d8) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole-d<sub>8</sub>
  • HY-W097867
    3-Desmethyl Gatifloxacin
    		Inhibitor
    3-Desmethyl Gatifloxacin (8-Methoxy Ciprofloxacin) induces DNA cleavage mediated by wild-type gyrase and Quinolone-resistant mutants. 3-Desmethyl Gatifloxacin can be used for research of drug resistance.
    3-Desmethyl Gatifloxacin
  • HY-182784
    Antibacterial agent 336
    		Inhibitor
    Antibacterial agent 336 is an antibacterical agent with broad-spectrum inhibitory activity against Gram-negative and Gram-positive bacteria. Antibacterial agent 336 binds tightly via its pyridine group to the carboxyl group, Lys-465 residue, and Leu-480 residue of the MsbA protein, interfering with bacterial outer membrane synthesis, and exerts concentration-dependent bactericidal activity against bacterial. Antibacterial agent 336 has low cytotoxicity to normal human liver cells. Antibacterial agent 336 can be used for the research of bacterial infections.
    Antibacterial agent 336
Cat. No. Product Name / Synonyms Application Reactivity