1. Metabolic Enzyme/Protease Anti-infection Cell Cycle/DNA Damage Immunology/Inflammation NF-κB
  2. Lactate Dehydrogenase Bacterial DNA/RNA Synthesis Reactive Oxygen Species (ROS)
  3. Antibacterial agent 306

Antibacterial agent 306 (Compound 8c), a lactate dehydrogenase inhibitor, is a highly effective antibacterial agent, especially effective against Gram-positive bacteria. Antibacterial agent 306 exhibits MIC against Staphylococcus aureus of as low as 1 μg/mL. Antibacterial agent 306 can not only damage membrane integrity and block the replication of DNA by intercalation, but also make reactive oxygen species (ROS) burst. Antibacterial agent 306 can be used for research on anti-multi-drug resistant bacteria.

For research use only. We do not sell to patients.

Antibacterial agent 306

Antibacterial agent 306 Chemical Structure

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Description

Antibacterial agent 306 (Compound 8c), a lactate dehydrogenase inhibitor, is a highly effective antibacterial agent, especially effective against Gram-positive bacteria. Antibacterial agent 306 exhibits MIC against Staphylococcus aureus of as low as 1 μg/mL. Antibacterial agent 306 can not only damage membrane integrity and block the replication of DNA by intercalation, but also make reactive oxygen species (ROS) burst. Antibacterial agent 306 can be used for research on anti-multi-drug resistant bacteria[1].

Molecular Weight

498.33

Formula

C23H20BrN3O5

SMILES

O=C(N/N=C/C1=CN(CCO)C2=C1C=C(Br)C=C2)COC3=CC(O4)=C(C=C3)C(C)=CC4=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Antibacterial agent 306
Cat. No.:
HY-180151
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