Cefonicid sodium (Standard)
Cefonicid sodium (Standard) is the analytical standard of Cefonicid sodium (HY-B1300). This product is intended for research and analytical applications. Cefonicid sodium is a long-acting cephalosporin antibiotic. Cefonicid sodium is also a non-competitive type I β-lactamase with a Ki value of 0.8 μM. Cefonicid sodium exhibits broad-spectrum antibacterial activity and is effective against a variety of Gram-positive and Gram-negative bacteria. Cefonicid sodium binds PBP1a, PBP1b, and PBP3, inhibiting peptidoglycan synthesis and leading to filamentation and lysis. Cefonicid sodium can be used for research on infections.
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 61270-78-8
- Formula: C18H16N6Na2O8S3
- Molecular Weight:586.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 61270-78-8
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Molecular Weight 586.53
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Formula C18H16N6Na2O8S3
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SMILES
O=C(C(N12)=C(CSC3=NN=NN3CS(=O)(O[Na])=O)CS[C@]2([H])[C@H](NC([C@H](O)C4=CC=CC=C4)=O)C1=O)O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Villa ML, et al. Interference of cephalosporins with immune response: effects of cefonicid on human T-helper cells. Int J Immunopharmacol. 1991;13(8):1099-1107. [Content Brief]
[4]. Saltiel E, et al. Cefonicid. A review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1986;32(3):222-259. [Content Brief]
[5]. Rake JB, et al. Affinity of cefonicid, a long-acting cephalosporin, for the penicillin-binding proteins of Escherichia coli K-12. The Journal of antibiotics. 1984 May;37(5):572-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Cefonicid sodium (Standard)
- 61270-78-8
- Reference Standards
- Bacterial
- Antibiotic
- Beta-lactamase
- Interleukin Related
- Penicillin-binding protein (PBP)
- β-lactamase
- IL
- Bacteroides fragilis
- CD4+ T-helper cells
- Enterobacter cloacae
- Klebsiella pneumoniae
- beta-lactamase
- interleukin-2
- penicillin-binding protein 1a
- penicillin-binding protein 1b
- penicillin-binding protein 3
- peptidoglycan synthesis
- Inhibitor
- inhibitor
- inhibit