2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-157533
    AcrB-IN-5
    		Inhibitor
    AcrB-IN-5 (compound 8) inhibits AcrB and blocks the efflux pump in a dose-dependent manner.
    AcrB-IN-5
  • HY-126462
    Lantic acid
    		Inhibitor
    Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents.
    Lantic acid
  • HY-149775
    Urease-IN-10
    Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner.
    Urease-IN-10
  • HY-181075
    Antibacterial agent 318
    		Inhibitor
    Antibacterial agent 318 is an antibacterial agent that binds to bacterial DNA, blocks its replication, and forms supramolecular complexes. Antibacterial agent 318 acts as an oxidative stress inducer, elevating intracellular reactive oxygen species (ROS) levels, oxidizing glutathione (GSH) to glutathione disulfide (GSSG), depleting cellular GSH reserves, and inducing bacterial cell death through oxidative damage. Antibacterial agent 318 disrupts the bacterial cell membrane and reduces bacterial metabolic activity. Antibacterial agent 318 exhibits rapid bactericidal activity, inhibits bacterial biofilm formation, and displays minimal cytotoxicity toward non-cancerous mammalian cells. Antibacterial agent 318 is applicable in research on drug-resistant bacterial infections.
    Antibacterial agent 318
  • HY-13062R
    Daunorubicin hydrochloride (Standard)
    		Inhibitor
    Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor.
    Daunorubicin hydrochloride (Standard)
  • HY-16752A
    Relebactam sodium
    		Inhibitor
    Relebactam sodium (MK-7655 sodium) is a potent and selective β-lactamase inhibitor with the activity of delaying the development of bacterial resistance to antibiotics. Relebactam sodium can bind to a variety of β-lactamases, thereby improving the efficacy of β-lactam antibiotics. Relebactam sodium shows good application potential in inhibiting complicated bacterial infections.
    Relebactam sodium
  • HY-117254
    BAS00127538
    BAS00127538 is a Lipid II inhibitor with antibacterial activity. As the first small molecule Lipid II inhibitor, BAS00127538 has a structure that is significantly different from compounds that naturally bind to Lipid II, such as vancomycin. The activity of BAS00127538 in terms of cytotoxicity and Lipid II binding is of great significance in antibacterial effects. Studies on BAS00127538 have shown that it has the potential to inhibit infection.
    BAS00127538
  • HY-179415
    DHFR-IN-24
    		Inhibitor
    DHFR-IN-24, a benzothiazole derivative, is a dihydrofolate reductase (DHFR) inhibitor. DHFR-IN-24 has intrinsic antibacterial activity against both Gram-positive and Gram-negative strains. DHFR-IN-24 synergistically combines DHFR inhibition with photodynamic therapy (PDT) for enhanced antibacterial activity against multidrug-resistant pathogens.
    DHFR-IN-24
  • HY-W705651
    Econazole nitrate-d6
    		Inhibitor
    Econazole nitrate-d6 is deuterium labeled Econazole (nitrate). Econazole nitrate is an imidazole class antifungal medication. Econazole nitrate also has antibacterial activity.
    Econazole nitrate-d<sub>6</sub>
  • HY-N14873
    Dienomycin A
    		Inhibitor
    Dienomycin A has anti-Gram-positive bacteria and mycobacterium activities.
    Dienomycin A
  • HY-N14587
    Oxypyrrolnitrin
    		Inhibitor
    Oxypyrrolnitrin is a nitrogen-containing heterocyclic antibiotic. Oxypyrrolnitrin has anti-Gram-positive bacteria, negative bacteria, mycobacterium and fungal effects.
    Oxypyrrolnitrin
  • HY-N14097
    Pyloricidin A2
    		Inhibitor
    Pyloricidin A2 is an antibiotic against Helicobacter pylori found in Bacillus sp. HC-70. Pyloricidin A2 has strong anti-Helicobacter pylori activity. Pyloricidin A2 has no activity against other bacteria and yeast.
    Pyloricidin A2
  • HY-N14833
    Naphthoquinomycin B
    		Inhibitor
    Naphthoquinomycin B is an Ansa antibiotic with anti-Gram-positive bacteria and fungi activity, and can inhibit the synthesis of E. coli fatty acids.
    Naphthoquinomycin B
  • HY-N14700
    3-O-Demethylmonensin A
    		Inhibitor
    3-O-Demethylmonensin A is a polyether antibiotic found in Streptomyces cinnamonensis LO-63.
    3-O-Demethylmonensin A
  • HY-N5201
    4"-Demethylgentamicin C1
    		Inhibitor
    4"-Demethylgentamicin C1 has anti-Gram-positive and negative bacteria activity.
    4
  • HY-17507E
    S-Pantoprazole sodium trihydrate
    S-Pantoprazole (sodium trihydrate) is related to Pantoprazole (HY-17507) that plays an important roles in gastric acid secretion disorder-related diseases, or as proton pump inhibitor.
    S-Pantoprazole sodium trihydrate
  • HY-180273
    Antibacterial agent 309
    		Inhibitor
    Antibacterial agent 309 (Compound C9) is an antibacterial agent, substrate of AcrB efflux pump. Antibacterial agent 309 promotes FtsZ polymerization. Antibacterial agent 309 demonstrates antibacterial activity against Erythromycin (HY-B0220)-resistant S. pyogenes 2 (MIC = 0.25 μg/mL), Penicillin-resistant S. aureus CI (MIC = 0.125 μg/mL), Penicillin-resistant S. epidermidis (MIC = 2 μg/mL). Antibacterial agent 309 exhibits weak antibacterial activity against the wild-type E. coli BW25113 MIC = 256 μg/mL).
    Antibacterial agent 309
  • HY-175539
    DNA gyrase/Topo IV-IN-2
    		Inhibitor
    DNA gyrase/Topo IV-IN-2 (Compound AK19) is an antibacterial agent with IC50 values of 0.783 μM and 7.136 μM against E. coli DNA gyrase and topoisomerase IV, respectively. DNA gyrase/Topo IV-IN-2 exhibits broad-spectrum antibacterial efficacy against both Gram-positive and Gram-negative pathogens. DNA gyrase/Topo IV-IN-2 can inhibit the biofilms of B. subtilis and MRSA, with an MIC of 1.9 μM against both B. subtilis and MRSA. DNA gyrase/Topo IV-IN-2 can be used in research related to anti-drug-resistant bacterial drugs.
    DNA gyrase/Topo IV-IN-2
  • HY-161097
    Antibacterial agent 171
    		Inhibitor
    Antibacterial agent 171 (Compound 28) is an antibacterial agent. Antibacterial agent 171 inhibits gram-negative bacteria.
    Antibacterial agent 171
  • HY-179383
    DprE1-IN-14
    		Inhibitor
    DprE1-IN-14 (Compound 77) is a DprE1 inhibitor, with an IC50 value of 2.5 nM for M. tb. DprE1-IN-14 exhibits anti-tuberculosis activity, with an MIC₉₀ of 0.3 μM for the M. tb mc26230 strain. DprE1-IN-14 mainly shows bacteriostatic activity, demonstrating a time-dependent bactericidal effect at 10-fold MIC concentrations. DprE1-IN-14 can be used in anti-tuberculosis research.
    DprE1-IN-14
Cat. No. Product Name / Synonyms Application Reactivity