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Relebactam sodium

(Synonyms: MK-7655 sodium)
33 Cited Publications
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Based on 33 publication(s) in Google Scholar

Relebactam sodium (MK-7655 sodium) is a potent and selective β-lactamase inhibitor with the activity of delaying the development of bacterial resistance to antibiotics. Relebactam sodium can bind to a variety of β-lactamases, thereby improving the efficacy of β-lactam antibiotics. Relebactam sodium shows good application potential in inhibiting complicated bacterial infections.

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  • CAS No.: 1502858-91-4
  • Formule: C12H19N4NaO6S
  • Masse moléculaire:370.36
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Relebactam sodium Chemical Structure
    Relebactam sodium Chemical Structure
  • Experimental Validation Results for Relebactam sodium
  • Experimental Validation Results for Relebactam sodium
  • Experimental Validation Results for Relebactam sodium
  • Experimental Validation Results for Relebactam sodium
  • Experimental Validation Results for Relebactam sodium
CAS No.: 1502858-91-4
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  • Relebactam sodium Chemical Structure
    Relebactam sodium Chemical Structure
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    Relebactam sodium purchased from MedChemExpress. Usage Cited in: Int J Antimicrob Agents. 2024 Aug;64(2):107206. [Abstract]

    Customer Validation
     The MultiRapid ATB NP test. Column D shows the solution with imipenem–relebactam (IPR, 12/4 mg/L);. Reference strain Escherichia coli ATCC 25922 was inoculated in wells A1–F1; Positive control resistant to all the antibiotics was inoculated in wells A2–F2; First tested strain (resistant to CZA, MEV, and IPR) was inoculated in wells A3–F3; Second tested strain (resistant to CZA and FDC) was inoculated in wells A4–F4; and NaCl 0.85% was inoculated in wells A5–F5. Bacterial growth is shown by a colour change of the medium from red to yellow.

  • 1/16

    Relebactam sodium purchased from MedChemExpress. Usage Cited in: Antimicrob Agents Chemother. 2023 Jun 15;67(6):e0160322. [Abstract]

    Customer Validation
     Difference between whole cells and isolated PBPs fraction unbound. P. aeruginosa PAO1 cultures (whole cells) and PBP-containing membrane preparations (isolated) were incubated for 15, 30, and 60 min in the presence of relebactam (REL), and afterwards isolated PBPs labeled with 25 μM Boc-FL.

  • 1/16

    Relebactam sodium purchased from MedChemExpress. Usage Cited in: Int J Antimicrob Agents. 2022 Nov-Dec;60(5-6):106669. [Abstract]

    Customer Validation
     The MICs of seven β-lactams with relebactam 8 mg/L against M. abscessus.

  • 1/16

    Relebactam sodium purchased from MedChemExpress. Usage Cited in: Int J Antimicrob Agents. 2022 Nov-Dec;60(5-6):106669. [Abstract]

    Customer Validation
     The MICs of seven β-lactams with relebactam 8 mg/L against M. massiliense.

  • 1/16

    Relebactam sodium purchased from MedChemExpress. Usage Cited in: Antibiotics (Basel). 2021 Nov 3;10(11):1341. [Abstract]

    Customer Validation
     Twenty-four-hour time–kill curves of aztreonam (ATM) and relebactam (REL), alone and in combination, on: C. amalonaticus N18; K. pneumoniae KL 12 SG; K. pneumoniae LC954/14.

  • Relebactam sodium