Daunorubicin hydrochloride (Standard)
Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 23541-50-6
- Formula: C₂₇H₃₀ClNO₁₀
- Molecular Weight:563.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-13062
Daunorubicin hydrochloride -
HY-16560
Camptothecin -
HY-10529
Betulinic acid -
HY-13062A
Daunorubicin -
HY-15142
Doxorubicin hydrochloride -
HY-13704
SN-38 -
HY-13753
Streptozotocin -
HY-10219
Rapamycin -
HY-15142R
Doxorubicin hydrochloride (Standard) -
HY-10529R
Betulinic acid (Standard) -
HY-16562
Irinotecan -
HY-17408
Mevastatin
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 23541-50-6
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Molecular Weight 563.98
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Formula C₂₇H₃₀ClNO₁₀
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SMILES
O=C(C(C(OC)=CC=C1)=C1C2=O)C3=C2C(O)=C(C[C@@](O)(C(C)=O)C[C@@H]4O[C@@]5([H])C[C@H](N)[C@H](O)[C@H](C)O5)C4=C3O.[H]Cl
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Synonyms
Daunomycin hydrochloride (Standard); RP 13057 hydrochloride (Standard); Rubidomycin hydrochloride (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lehmann M, et al. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environ Mol Mutagen. 2004;43(4):250-7. [Content Brief]
[2]. Dano K, et al. Inhibition of DNA and RNA synthesis by daunorubicin in sensitive and resistant Ehrlich ascites tumor cells in vitro. Cancer Res. 1972 Jun;32(6):1307-14. [Content Brief]
[3]. Svensson SP, et al. Melanin inhibits cytotoxic effects of Doxorubicin and Daunorubicin in MOLT 4 cells. Pigment Cell Res. 2003 Aug;16(4):351-4 [Content Brief]
[4]. Gervasoni JE Jr, et al. An effective in vitro antitumor response against human pancreatic carcinoma with paclitaxel and Daunorubicin by induction of both necrosis and apoptosis. Anticancer Res. 2004 Sep-Oct;24(5A):2617-26 [Content Brief]
[5]. Arozal W, et al. Telmisartan prevents the progression of renal injury in daunorubicin rats with the alteration of angiotensin II and endothelin-1 receptor expression associated with its PPAR-γ agonist actions. Toxicology. 2011 Jan 11;279(1-3):91-9. [Content Brief]
[6]. Emeline Bollaert, et al. MiR-15a-5p Confers Chemoresistance in Acute Myeloid Leukemia by Inhibiting Autophagy Induced by Daunorubicin. Int J Mol Sci. 2021 May 13;22(10):5153. [Content Brief]
[7]. Cheng Wu, et al. Doxorubicin suppresses chondrocyte differentiation by stimulating ROS production. Eur J Pharm Sci. 2021 Dec 1;167:106013. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Daunorubicin hydrochloride (Standard) Related Classifications
HY-13062R Related Classifications
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Keywords
- Daunorubicin hydrochloride (Standard)
- 23541-50-6
- Daunomycin hydrochloride (Standard)
- RP 13057 hydrochloride (Standard)
- Rubidomycin hydrochloride (Standard)
- Reference Standards
- Topoisomerase
- DNA/RNA Synthesis
- ADC Payloads
- Bacterial
- Autophagy
- Apoptosis
- Antibiotic
- Anti-tumor
- Ehrlich ascites tumor
- pancreatic carcinoma leukemia
- cytotoxin
- Molt-4 cell
- L3.6 cell
- K562 cells
- chamomile
- Inhibitor
- inhibitor
- inhibit