1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Dopamine Receptor
  4. Dopamine Receptor Isoform
  5. Dopamine Receptor Agonist

Dopamine Receptor Agonist

Dopamine Receptor Agonists (59):

Cat. No. Product Name Effect Purity
  • HY-12520A
    SKF 38393 hydrochloride
    Agonist 99.44%
    SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM.
  • HY-10435A
    SKF-82958 hydrobromide
    Agonist 99.59%
    SKF-82958 ((±)-SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM).
  • HY-70081A
    Sumanirole maleate
    Agonist ≥99.0%
    Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM.
  • HY-B0735A
    Fenoldopam mesylate
    Agonist 99.86%
    Fenoldopam mesylate (SKF-82526) is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM).
  • HY-17355
    Pramipexole dihydrochloride
    Agonist ≥98.0%
    Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively.
  • HY-B1752A
    Quinpirole Hydrochloride
    Agonist 99.52%
    Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor.
  • HY-128770
    Agonist 99.81%
    LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM).
  • HY-21098A
    PD-168077 maleate
    Agonist 98.74%
    PD-168077 maleate is a selective dopamine D4 receptor agonist, with a Ki of 9 nM.
  • HY-101299B
    Dihydrexidine hydrochloride
    Agonist 99.21%
    Dihydrexidine hydrochloride (DAR-0100 hydrochloride) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist, with an IC50 of 10 nM for D1 receptor.
  • HY-17355A
    Dexpramipexole dihydrochloride
    Agonist 99.71%
    Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and weak non-ergoline dopamine agonist.
  • HY-110080
    Lisuride maleate
    Agonist 99.97%
    Lisuride (maleate) is a potent agonist of dopamine with a probably direct action on dopaminergic receptors.
  • HY-125751
    Agonist 99.53%
    UCSF924 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM.
  • HY-110000
    (+)-PD 128907 hydrochloride
    Agonist 99.85%
    (+)-PD 128907 hydrochloride is a selective dopamine D2/D3 receptor agonist, with Kis of 1.7, 0.84 nM for human and rat D3 receptors, 179, 770 n M for human and rat D3 receptors, respectively.
  • HY-13736A
    Quinagolide hydrochloride
    Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist.
  • HY-103410
    Carmoxirole hydrochloride
    Agonist 98.04%
    Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo.
  • HY-103416
    A-77636 hydrochloride
    Agonist 98.00%
    A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity.
  • HY-106094
    CY 208-243
    Agonist 99.98%
    CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity.
  • HY-128121
    Agonist 99.73%
    MLS1547 is a highly efficacious G protein-biased dopamine D2 receptor (D2R) agonist (Ki=1.2 μM).
  • HY-106100A
    Roxindole hydrochloride
    Agonist 99.48%
    Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range.
  • HY-101384A
    Ro 10-5824 dihydrochloride
    Agonist 99.93%
    Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM.