1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  3. HSP
  4. HSP Inhibitors

HSP Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

HSPA5

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

HSP Inhibitors, Antagonists & Activators
Product Name HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5 Purity
Tamoxifen    
HSP90
        99.95%
Tanespimycin    
HSP90, IC50: 5 nM
        99.03%
Luminespib  
TRAP-1, IC50: 85 nM
HSP90α, IC50: 7.8 nM
HSP90β, IC50: 21 nM
GRP94, IC50: 535 nM
        99.81%
Geldanamycin    
HSP90, Kd: 1.2 μM
        99.78%
Rocaglamide        
HSF1, IC50: 50 nM
    99.34%
AMP-PCP disodium    
HSP90, Kd: 3.8 μM
        >99.0%
ML346  
HSP70, EC50: 4.6 μM (HeLa cells)
          >98.0%
Gamitrinib TPP    
HSP90
       
Ganetespib    
HSP90
        99.94%
Gamitrinib TPP hexafluorophosphate    
HSP90
        99.26%
Alvespimycin hydrochloride    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
        98.72%
VER-155008  
HSP70, IC50: 0.5 μM
HSC70, IC50: 2.6 μM
Grp78, IC50: 2.6 μM
          99.64%
Tamoxifen Citrate    
HSP90
        99.55%
Onalespib    
HSP90, Kd: 0.71 nM
        99.96%
Apoptozole  
HSP70, Kd: 0.14 μM
HSC70, Kd: 0.21 μM
          99.97%
BIIB021    
HSP90, Ki: 1.7 nM
HSP90, EC50: 38 nM
        99.93%
PU-WS13  
TRAP-1, EC50: 7.3 μM
GRP94, EC50: 0.22 μM
HSP90α, EC50: 27.3 μM
HSP90β, EC50: 41.8 μM
        99.34%
KRIBB11        
HSF1, IC50: 1.2 μM
    99.12%
HSF1A        
HSF1
    99.43%
KNK437
HSP40
HSP70
 
HSP105
      >98.0%
Pifithrin-μ  
HSP70
          98.31%
Debio 0932    
HSP90α, IC50: 100 nM
HSP90β, IC50: 103 nM
        99.97%
NVP-HSP990  
TRAP1 ATPase, IC50: 320 nM
HSP90α, IC50: 0.6 nM
HSP90β, IC50: 0.8 nM
GRP94, IC50: 8.5 nM
        98.98%
Teprenone          
HSP
  98.12%
XL888    
HSP90, IC50: 24 nM
        99.24%
Arimoclomol maleate          
HSP
  99.96%
MKT-077  
HSP70
          >98.0%
Grp94 Inhibitor-1    
GRP94, IC50: 2 nM
        99.18%
TAS-116    
HSP90α, Ki: 34.7 nM
HSP90β, Ki: 21.3 nM
        98.96%
CCT251236  
HSP72, IC50: 19 nM (SK-OV-3 cells)
          >99.0%
TRC051384  
HSP70
          98.19%
KW-2478    
HSP90α, IC50: 3.8 nM
        >98.0%
Radicicol    
HSP90, IC50: 1 μM
        >99.0%
VER-82576  
TRAP-1, IC50: 5.5 μM
HSP90β, IC50: 58 nM
GRP94, IC50: 4.1 μM
        99.56%
HSP70-IN-1  
HSP70
          98.01%
VER-50589    
HSP90, IC50: 21 nM
        99.85%
VER-49009    
HSP90, IC50: 25 nM
        99.26%
Ethoxyquin    
HSP90
        98.05%
Col003
HSP47, IC50: 1.8 μM
            99.30%
Alvespimycin    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
       
HM03            
HSPA5
98.06%
Cucurbitacin D    
HSP90
        99.20%
SNX-5422 Mesylate    
HSP90, Kd: 41 nM
       
Arimoclomol          
HSP
 
Arimoclomol citrate          
HSP
 
YZ129    
HSP90
       
Shepherdin (79-87)    
HSP90
       
Eupalinolide A        
HSF1
   
NMS-E973    
HSP90α, DC50: 10 nM
       
Geldanamycin-FITC    
HSP90
       
17-AEP-GA    
HSP90
       
HS-27    
HSP90
       
17-GMB-APA-GA    
HSP90
       
Tamoxifen-​d5    
HSP90
       
Dihydroberberine    
HSP90
       
AMP-PCP    
HSP90, Kd: 3.8 μM
       
MPC-0767    
HSP90
       
Retaspimycin    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM
       
Bimoclomol          
HSP