1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. HSP Inhibitors

HSP Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

HSP Inhibitors & Activators
Product Name HSP40 HSP70 HSP90 HSP105 HSF1 HSP Purity
17-AAG    
HSP90, IC50: 5 nM
      99.03%
Ganetespib    
HSP90
      99.56%
Triptolide    
HSP90
      99.83%
NVP-AUY922  
TRAP-1, IC50: 85 nM
HSP90α, IC50: 7.8 nM
HSP90β, IC50: 21 nM
GRP94, IC50: 535 nM
      99.14%
Geldanamycin    
HSP90, Kd: 1.2 μM
      99.78%
XL888    
HSP90, IC50: 24 nM
      99.24%
Pifithrin-μ  
HSP70
        98.31%
MKT-077  
HSP70
       
Rocaglamide        
HSF1, IC50: 50 nM
  99.40%
AT13387    
HSP90, Kd: 0.71 nM
      99.64%
VER-155008  
HSP70, IC50: 0.5 μM
HSC70, IC50: 2.6 μM
Grp78, IC50: 2.6 μM
        99.64%
Retaspimycin Hydrochloride    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM
      >95.0%
Teprenone          
HSP
>98.0%
BIIB021    
HSP90, Ki: 1.7 nM
      99.62%
Alvespimycin hydrochloride    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
      99.32%
Debio 0932    
HSP90α, IC50: 100 nM
HSP90β, IC50: 103 nM
      99.44%
KRIBB11        
HSF1, IC50: 1.2 μM
  99.04%
NVP-HSP990  
TRAP1 ATPase, IC50: 320 nM
HSP90α, IC50: 0.6 nM
HSP90β, IC50: 0.8 nM
GRP94, IC50: 8.5 nM
      98.98%
Apoptozole  
HSP70, Kd: 0.14 μM
HSC70, Kd: 0.21 μM
        99.57%
PU-WS13  
TRAP-1, EC50: 7.3 μM
GRP94, EC50: 0.22 μM
HSP90α, EC50: 27.3 μM
HSP90β, EC50: 41.8 μM
      95.69%
KNK437
HSP40
HSP70
 
HSP105
    >98.0%
HSF1A        
HSF1
  99.33%
NVP-BEP800  
TRAP-1, IC50: 5.5 μM
HSP90β, IC50: 58 nM
GRP94, IC50: 4.1 μM
      99.48%
TRC051384  
HSP70
        97.40%
HSP70-IN-1  
HSP70
        98.05%
CCT251236  
HSP72, IC50: 19 nM (SK-OV-3 cells)
        99.03%
17-AAG Hydrochloride    
HSP90, IC50: 5 nM
      98.23%
Alvespimycin    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
     
Ethoxyquin    
HSP90
      98.05%
VER-50589    
HSP90, IC50: 21 nM
      >98.0%
VER-49009    
HSP90, IC50: 25 nM
     
PF-04929113 Mesylate    
HSP90, Kd: 41 nM
     
KW-2478    
HSP90α, IC50: 3.8 nM
     
ML346  
HSP70, EC50: 4.6 μM (HeLa cells)
        >98.0%
Retaspimycin    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM
     
TAS-116    
HSP90α, Ki: 34.7 nM
HSP90β, Ki: 21.3 nM
     
Bimoclomol          
HSP