1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  3. HSP
  4. HSP Inhibitors

HSP Inhibitors

HSP40

HSP70

HSP90

HSP105

HSF1

HSP

HSPA5

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

HSP Inhibitors, Antagonists & Activators
Product Name HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5 Purity
Tamoxifen    
HSP90
        99.92%
Tanespimycin    
HSP90, IC50: 5 nM
        ≥98.0%
Geldanamycin    
HSP90, Kd: 1.2 μM
        ≥98.0%
Ganetespib    
HSP90
        99.84%
Chetomin    
HSP90
        ≥99.0%
Gedunin    
HSP90
       
Rocaglamide        
HSF1, IC50: 50 nM
    99.34%
Luminespib    
HSP90α, IC50: 7.8 nM
HSP90β, IC50: 21 nM
GRP94, IC50: 535 nM
        ≥98.0%
VER-155008  
HSP70, IC50: 0.5 μM
HSC70, IC50: 2.6 μM
Grp78, IC50: 2.6 μM
          99.87%
Gamitrinib TPP hexafluorophosphate    
HSP90
        ≥98.0%
Tamoxifen Citrate    
HSP90
        ≥99.0%
Alvespimycin hydrochloride    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
        98.68%
Arimoclomol maleate          
HSP
  ≥98.0%
Apoptozole  
HSP70, Kd: 0.14 μM
HSC70, Kd: 0.21 μM
          99.81%
Onalespib    
HSP90, Kd: 0.71 nM
        99.96%
Pimitespib    
HSP90α, Ki: 34.7 nM
HSP90β, Ki: 21.3 nM
        99.31%
Grp94 Inhibitor-1    
GRP94, IC50: 2 nM
        98.63%
PU-WS13    
GRP94, EC50: 0.22 μM
HSP90α, EC50: 27.3 μM
HSP90β, EC50: 41.8 μM
        99.34%
BIIB021    
HSP90, Ki: 1.7 nM
HSP90, EC50: 38 nM
        99.93%
Pifithrin-μ  
HSP70
          98.31%
MKT-077  
HSP70
          ≥98.0%
HSF1A        
HSF1
    99.43%
KNK437
HSP40
HSP70
 
HSP105
      ≥98.0%
NVP-HSP990    
HSP90α, IC50: 0.6 nM
HSP90β, IC50: 0.8 nM
GRP94, IC50: 8.5 nM
        99.77%
TRC051384  
HSP70
          98.19%
ML346  
HSP70, EC50: 4.6 μM (HeLa cells)
          ≥98.0%
KRIBB11        
HSF1, IC50: 1.2 μM
    99.12%
Debio 0932    
HSP90α, IC50: 100 nM
HSP90β, IC50: 103 nM
        99.97%
HM03            
HSPA5
98.06%
Radicicol    
HSP90, IC50: 1 μM
        ≥99.0%
CCT251236  
HSP72, IC50: 19 nM (SK-OV-3 cells)
          ≥99.0%
Retaspimycin Hydrochloride    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM
        98.35%
AMP-PCP disodium    
HSP90, Kd: 3.8 μM
        ≥99.0%
VER-82576    
HSP90β, IC50: 58 nM
GRP94, IC50: 4.1 μM
        99.56%
XL888    
HSP90, IC50: 24 nM
        99.62%
Col003
HSP47, IC50: 1.8 μM
            ≥98.0%
Teprenone          
HSP
  99.13%
KW-2478    
HSP90α, IC50: 3.8 nM
        98.62%
HSP70-IN-1  
HSP70
          98.01%
VER-49009    
HSP90, IC50: 25 nM
        99.39%
Ethoxyquin    
HSP90
        98.29%
VER-50589    
HSP90, IC50: 21 nM
        99.85%
Cucurbitacin D    
HSP90
        ≥98.0%
Aminohexylgeldanamycin    
HSP90
       
HS-27    
HSP90
        98.48%
Eupalinolide A        
HSF1
    99.92%
Alvespimycin    
HSP90, EC50: 62 nM
GRP94, EC50: 65 nM
       
Gamitrinib TPP    
HSP90
       
NMS-E973    
HSP90α, DC50: 10 nM
       
3-Phenyltoxoflavin    
HSP90, Kd: 585 nM
        99.73%
Geldanamycin-FITC    
HSP90
       
Bimoclomol          
HSP
  99.19%
Arimoclomol          
HSP
 
Arimoclomol citrate          
HSP
 
YZ129    
HSP90
       
NCT-58    
HSP90
       
Shepherdin (79-87)    
HSP90
       
Aminohexylgeldanamycin hydrochloride    
HSP90
       
17-AEP-GA    
HSP90
       
17-GMB-APA-GA    
HSP90
       
Tamoxifen-​d5    
HSP90
       
Dihydroberberine    
HSP90
       
AMP-PCP    
HSP90, Kd: 3.8 μM
       
Conglobatin    
HSP90
       
MPC-0767    
HSP90
       
Retaspimycin    
HSP90, EC50: 119 nM
GRP94, EC50: 119 nM