2. Signaling Pathways
  3. Anti-infection
  4. HSV

HSV

Herpes simplex virus

HSV

Related Products

PDF 0.38 MB

HSV (Herpes simplex virus) can be spread when an infected person is producing and shedding the virus. Herpes simplex can be spread through contact with saliva, such as sharing drinks. Symptoms of herpes simplex virus infection include watery blisters in the skin or mucous membranes of the mouth, lips or genitals. Lesions heal with ascab characteristic of herpetic disease. As neurotropic and neuroinvasive viruses, HSV-1 and -2 persist in the body by becoming latent and hiding from the immune system in the cell bodies of neurons. After the initial or primary infection, some infected people experience sporadic episodes of viral reactivation or outbreaks.

HSV Isoform Specific Products:

HSV Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0277AR
    Vidarabine phosphate (Standard)
    		Inhibitor
    Vidarabine phosphate (ara-AMP; ara-A 5'-monophosphate) (Standard) is the analytical standard of Vidarabine phosphate. This product is intended for research and analytical applications. Vidarabine phosphate is a purine nucleoside antiviral agent and a prodrug of Vidarabine (HY-B0277). Vidarabine phosphate is rapidly converted into the antiviral active Vidarabine in vivo, which selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis.
    Vidarabine phosphate (Standard)
  • HY-177640B
    Lepodisiran sodium scrambled negative control
    		Inhibitor
    Lepodisiran sodium scrambled negative control is the sequence scrambled negative control of Lepodisiran sodium.
    Lepodisiran sodium scrambled negative control
  • HY-N12191
    Cangorinine E-1
    		Inhibitor
    Cangorinine E-1 (compound 11) is a dihydroagarofuran derivative of the sesquiterpenoid family. Cangorinine E-1 exhibits weak inhibitory effects on herpes simplex virus type II (HSV).
    Cangorinine E-1
  • HY-122704
    Surfen
    		Inhibitor
    Surfen is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 μM. Surfen inhibits HSV-1 viral infection. Surfen inhibits neural differentiation, delays remyelination, and alleviates EAE.
    Surfen
  • HY-128744R
    Phosphonoacetic acid (Standard)
    		Inhibitor
    Phosphonoacetic acid (Standard) is the analytical standard of Phosphonoacetic acid (HY-128744). This product is intended for research and analytical applications. Phosphonoacetic acid is an endogenous metabolite and antiviral agent. Phosphonoacetic acid is active against orthopoxviruses and herpes viruses. Phosphonoacetic acid can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, and affect the synthesis of late viral proteins.
    Phosphonoacetic acid (Standard)
  • HY-W770677
    9-Carboxymethoxymethylguanine-13C2,15N
    9-Carboxymethoxymethylguanine-13C2,15N is the 13C- and 15N-labeled 9-Carboxymethoxymethylguanine (HY-137181). 9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent.
    9-Carboxymethoxymethylguanine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-116758
    16,16-Dimethyl prostaglandin A1
    		Inhibitor
    16,16-Dimethyl prostaglandin A1 (di-Me-PGA1) is a prostaglandin analog that can inhibit DNA synthesis in Lewis lung carcinoma and B 16 amelanotic melanoma cells. 16,16-Dimethyl prostaglandin A1 also inhibits viral replication in both HSV and HIV-1 infection systems.
    16,16-Dimethyl prostaglandin A1
  • HY-A0061S
    Trifluridine-13C,15N2
    Trifluridine-13C,15N2 is the 13C and 15N labeled Trifluridine. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity.
    Trifluridine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-137181
    9-Carboxymethoxymethylguanine
    		Inhibitor
    9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent.
    9-Carboxymethoxymethylguanine
  • HY-126375
    Cbz-​Valaciclovir
    		98.09%
    Cbz-Valaciclovir (Benzyloxycarbonyl valacyclovir) can be used to prepare Valaciclovir (HY-17425) and for antiviral research.
    Cbz-​Valaciclovir
  • HY-A0181S4
    Adenosine monophosphate-13C10,15N5,d12 dilithium
    		Inhibitor
    Adenosine monophosphate-13C10,15N5,d12 (AMP-13C10,15N5,d12) dilithium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
    Adenosine monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub>,d<sub>12</sub> dilithium
  • HY-145246
    Biotin-PEG8-Vidarabine
    		Inhibitor
    Biotin-PEG8-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses.
    Biotin-PEG8-Vidarabine
  • HY-B0275S
    Oxytetracycline-d6
    		Inhibitor
    Oxytetracycline-d6 is deuterium labeled Oxytetracycline. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.
    Oxytetracycline-d<sub>6</sub>
  • HY-P4773
    HSV-1 Protease substrate
    HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (kcat/Km) at pH 7.5 for cleavage is 5.2 M-1 s-1.
    HSV-1 Protease substrate
  • HY-177638
    ISIS 1082
    		Inhibitor
    ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
    ISIS 1082
  • HY-P11022
    TL-119
    		Inhibitor
    TL-119 (A-3302-B) is a polypeptide. TL-119 can be isolated from the bacteria Micromonospora sp. MAG 9-7 and Saccharomonospora sp. CNQ-490. TL-119 inhibits TRPV-1. TL-119 exhibits antiviral activity against HSV-2. TL-119 possesses anticancer activity against gastric cancer and colorectal cancer.
    TL-119
  • HY-N13837
    2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol
    2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol (Compound 1) is a 9,10-dihydrophenanthrene derivative. 2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol can be isolated from Juncus compressus. 2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol exhibits anticancer activity against cervical and ovarian cancers. 2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol can be used for HSV-2 virus research.
    2-Methoxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthren-7-ol
  • HY-B0275S1
    Oxytetracycline-d3
    		Inhibitor
    Oxytetracycline-d3 is the deuterium labeled Oxytetracycline (HY-B0275). Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.
    Oxytetracycline-d<sub>3</sub>
  • HY-101848A
    16-epi-Latrunculin B
    		Inhibitor
    16-epi-latrunculin B is anticancer agent, which can inhibit the growth of HeLa cells with IC50 value of 3.9 uM. 16-epi-latrunculin B has antiviral activity against HSV-1 (ED50 of 1 µg/mL).
    16-epi-Latrunculin B
  • HY-P5642
    Retrocyclin-101
    		Inhibitor
    Retrocyclin-101 (RC-101) is a synthetic cyclic θ-defensin, a broad-spectrum antimicrobial peptide with anti-pathogen (covering viruses, bacteria and fungi) activity and anti-inflammatory activity. Retrocyclin-101 exhibits significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus and others. Retrocyclin-101 inhibits TLR4 and TLR2-mediated signal transduction and reduces pro-inflammatory cytokine expression.
    Retrocyclin-101
HSV Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.