16-epi-Latrunculin B
16-epi-latrunculin B is anticancer agent, which can inhibit the growth of HeLa cells with IC50 value of 3.9 uM. 16-epi-latrunculin B has antiviral activity against HSV-1 (ED50 of 1 µg/mL).
For research use only. We do not sell to patients.
- CAS No.: 444911-05-1
- Formula: C20H29NO5S
- Molecular Weight:395.51
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
38 μM
Compound: 3
|
Cytotoxicity against human HCT116 cells after 3 days by trypan blue assay
Cytotoxicity against human HCT116 cells after 3 days by trypan blue assay
|
[PMID: 18942825] |
| MDA-MB-435 | IC50 |
17 μM
Compound: 3
|
Cytotoxicity against human MDA-MB-435 cells 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 cells 48 hrs by SRB assay
|
[PMID: 18942825] |
Chemical Information
-
CAS No. 444911-05-1
-
Molecular Weight 395.51
-
Formula C20H29NO5S
-
SMILES
O=C1SC[C@H]([C@]2(O)O[C@]3([H])CC[C@H](C)/C=C\CC/C(C)=C\C(O[C@@](C3)([H])C2)=O)N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Diaa T A Youssef, et al. Magnificines A and B, Antimicrobial Marine Alkaloids Featuring a Tetrahydrooxazolo[3,2-a]azepine-2,5( 3H,6H)-dione Backbone from the Red Sea Sponge Negombata magnifica. Mar Drugs. 2021 Apr 12;19(4):214. [Content Brief]
[2]. Thomas R Hoye, et al. Toward computing relative configurations: 16-epi-latrunculin B, a new stereoisomer of the actin polymerization inhibitor latrunculin B. J Am Chem Soc. 2002 Jun 26;124(25):7405-10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
16-epi-Latrunculin B Related Classifications
HY-101848A Related Classifications
Powered by Bioz