Phosphonoacetic acid (Standard)
Phosphonoacetic acid Standard is the analytical standard of Phosphonoacetic acid (HY-128744). This product is intended for research and analytical applications. Phosphonoacetic acid is a potent antiviral agent. Phosphonoacetic acid inhibits a variety of herpesviruses, orthopoxviruses, and retroviruses. Phosphonoacetic acid strongly inhibits viral and cellular DNA polymerase, reverse transcriptase, and terminal deoxynucleotidyl transferase activities in a non-competitive or uncompetitive manner by binding to the pyrophosphate site of the enzyme. Phosphonoacetic acid is useful for research related to lymphoid leukemia, herpesvirus infection, and vaccinia virus skin lesions.
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 4408-78-0
- Formula: C2H5O5P
- Molecular Weight:140.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 4408-78-0
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Molecular Weight 140.03
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Formula C2H5O5P
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SMILES
O=C(O)CP(O)(O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[3]. Honess RW, et al. Herpes simplex virus resistance and sensitivity to phosphonoacetic acid. Journal of virology. 1977 Feb;21(2):584-600. [Content Brief]
[4]. Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral research. 2003 Jan;57(1-2):41-52. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phosphonoacetic acid (Standard) Related Classifications
HY-128744R Related Classifications
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Keywords
- Phosphonoacetic acid (Standard)
- 4408-78-0
- Reference Standards
- HSV
- Orthopoxvirus
- DNA/RNA Synthesis
- Reverse Transcriptase
- viral DNA replication
- reverse transcriptase
- herpesvirus
- HHV-6
- BHK-21 cells
- mouse L1210 cell
- human terminal deoxynucleotidyltransferase
- cord blood mononuclear cell
- lymphoid leukemia
- DNA polymerase
- Inhibitor
- inhibitor
- inhibit