4408-78-0
4408-78-0
Chemical Structure
Phosphonoacetic acid
- CAS No.: 4408-78-0
- Formula:C2H5O5P
- Molecular Weight:140.03
IUPAC Name: 2-phosphonoacetic acid
InChIKey: XUYJLQHKOGNDPB-UHFFFAOYSA-N
SMILES: O=C(O)CP(O)(O)=O
Biological Activity: Phosphonoacetic acid is an endogenous metabolite and antiviral agent. Phosphonoacetic acid is active against orthopoxviruses and herpes viruses. Phosphonoacetic acid can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, and affect the synthesis of late viral proteins[1][2].
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Phosphonoacetic acid | 98.0% | Phosphonoacetic acid is an endogenous metabolite and antiviral agent. Phosphonoacetic acid is active against orthopoxviruses and herpes viruses. Phosphonoacetic acid can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, and affect the synthesis of late viral proteins. | ||||||||||||||||||||
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Phosphonoacetic acid (Standard) | ≥98% | Phosphonoacetic acid (Standard) is the analytical standard of Phosphonoacetic acid (HY-128744). This product is intended for research and analytical applications. Phosphonoacetic acid is an endogenous metabolite and antiviral agent. Phosphonoacetic acid is active against orthopoxviruses and herpes viruses. Phosphonoacetic acid can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, and affect the synthesis of late viral proteins. | ||||||||||||||||||||
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References
- [1]. Honess RW, et al. Herpes simplex virus resistance and sensitivity to phosphonoacetic acid. J Virol. 1977 Feb;21(2):584-600. [Content Brief]
- [2]. Donald F Smee, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52. [Content Brief]
